100557-22-0

Basic information

• Product Name: 4-Amino-1-(phenylsulfonyl)-indole
• Synonyms: 4-Amino-1-(phenylsulfonyl)-indole
• CAS NO: 100557-22-0
• Molecular Formula: C₁₄H₁₂N₂O₂S
• Molecular Weight: 272.32228
• Product Categories: Heterocycles
• Mol File: 100557-22-0.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-Amino-1-(phenylsulfonyl)-indole(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Amino-1-(phenylsulfonyl)-indole(100557-22-0)
• EPA Substance Registry System: 4-Amino-1-(phenylsulfonyl)-indole(100557-22-0)

Safety Data

• Hazardous Substances Data: 100557-22-0(Hazardous Substances Data)

Usage

General Description

4-Amino-1-(phenylsulfonyl)-indole is a heterocyclic compound with the molecular formula C14H11N3O2S. It is an indole derivative with a phenylsulfonyl substituent at the 1-position and an amino group at the 4-position. This chemical has potential applications in medicinal chemistry and drug development due to its structural features and potential pharmacological properties. It is important for researchers to thoroughly study this compound in order to understand its biological activity, potential therapeutic uses, and potential side effects. Overall, 4-Amino-1-(phenylsulfonyl)-indole is a compound of interest in the field of medicinal chemistry and may have promising applications in drug discovery and development.

Upstream product

• 98-09-9 benzenesulfonyl chloride 
• 4769-97-5 4-nitro-1H-indoIe 
• 850655-62-8 4-nitro-1-(phenylsulfonyl)-1H-indole 
• 95969-08-7 1-benzenesulfonyl-5-chloro-4-oxo-4,5,6,7-tetrahydroindole 

Downstream Products

• 1022158-71-9 6-(1-benzenesulfonyl-1H-indol-4-ylamino)-2-chloro-5-nitro-pyrimidine-4-carboxylic acid methyl ester 
• 850655-63-9 N-(1-benzenesulfonyl-1H-indol-4-yl)-2-bromoacetamide 

Relevant articles and documents

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Mutants of the FLT3 receptor tyrosine kinase (RTK) with duplications in the juxtamembrane domain (FLT3-ITD) act as drivers of acute myeloid leukemia (AML). Potent tyrosine kinase inhibitors (TKi) of FLT3-ITD entered clinical trials and showed a promising,

TETRAHYDROISOQUINOLINE DERIVATIVES

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PROCESS FOR THE PREPARATION OF 2,4-DICHLORO-7H-PYRROLO[2,3H]QUINAZOLINE

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