1006-24-2 Usage
Uses
Used in Pharmaceutical Industry:
3-Ethyl-6-methylpyrimidine-2,4(1H,3H)-dione is used as an intermediate in the synthesis of various pharmaceuticals for its potential to act as a bronchodilator, anti-inflammatory, and anti-asthmatic agent. Its anticonvulsant and analgesic activities also make it a promising candidate for the development of new therapeutic agents.
Used in Agrochemical Industry:
3-Ethyl-6-methylpyrimidine-2,4(1H,3H)-dione is used as an intermediate in the synthesis of agrochemicals due to its potential as an antimicrobial and antifungal agent. This allows for the development of new agents to combat microbial and fungal infections in agriculture.
Used in Respiratory Applications:
3-Ethyl-6-methylpyrimidine-2,4(1H,3H)-dione is used as a bronchodilator for the treatment of respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD), helping to relax and widen the airways for easier breathing.
Used in Anti-inflammatory and Analgesic Applications:
3-Ethyl-6-methylpyrimidine-2,4(1H,3H)-dione is used as an anti-inflammatory and analgesic agent for the management of pain and inflammation in various conditions, including arthritis and other inflammatory disorders.
Used in Anticonvulsant Applications:
3-Ethyl-6-methylpyrimidine-2,4(1H,3H)-dione is used as an anticonvulsant agent for the treatment of seizure disorders, helping to prevent or reduce the frequency and severity of seizures.
Used in Antimicrobial and Antifungal Applications:
3-Ethyl-6-methylpyrimidine-2,4(1H,3H)-dione is used as an antimicrobial and antifungal agent for the treatment of bacterial and fungal infections, both in humans and in agriculture, to control the growth of harmful microorganisms.
Check Digit Verification of cas no
The CAS Registry Mumber 1006-24-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,0,0 and 6 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1006-24:
(6*1)+(5*0)+(4*0)+(3*6)+(2*2)+(1*4)=32
32 % 10 = 2
So 1006-24-2 is a valid CAS Registry Number.
InChI:InChI=1/C7H10N2O2/c1-3-9-6(10)4-5(2)8-7(9)11/h4H,3H2,1-2H3,(H,8,11)
1006-24-2Relevant academic research and scientific papers
A diversity of alkylation/acylation products of uracil and its derivatives: Synthesis and a structural study
Michalak, Olga,Cmoch, Piotr,Krzeczyński, Piotr,Cybulski, Marcin,Le?, Andrzej
, p. 354 - 362 (2019/01/10)
tert-Butyl dicarbonate (Boc2O) and ethyl iodide (EtI) reactions with uracil (U), thymine (T) and 6-methyluracil (6-MU) were performed following routine procedures in pyridine/DMF solvents and with DMAP as the catalyst. Among 20 synthesized compounds, a derivative of 6-methyluracil substituted by the Boc-pyridine moiety at the C5 position appeared unexpectedly. The NMR spectra confirmed the molecular structure of all uracil derivatives. Parallel quantum mechanical DFT calculations supported the experimental findings.
A2B ADENOSINE RECEPTOR ANTAGONISTS
-
Page/Page column 34, (2008/06/13)
Disclosed are novel compounds that are A2B adenosine receptor antagonists having the following structure (I) wherein R1 and R2 are independently chosen from hydrogen, optionally substituted alkyl, optionally substituted cycloalkyl, optionally substituted aryl, and optionally substituted heteroaryl, and R4 is an optionally substituted heteroaryl moiety. The compounds of the invention are useful for treating various disease states, including asthma, chronic obstructive pulmonary disorder, pulmonary inflammation, emphysema, diabetic disorders, inflammatory gastrointestinal tract disorders, immunological/inflammatory disorders, cardiovascular diseases, neurological disorders, and diseases related to angiogenesis.
HSAB driven chemoselectivity in alkylation of uracil derivatives. A high yielding preparation of 3-alkylated and unsymmetrically 1,3-dialkylated uracils
Gambacorta, Augusto,Farah, Mohamed Elmi,Tofani, Daniela
, p. 12615 - 12628 (2007/10/03)
A qualitative hardness scale (N134) has been found for the conjugated bases of 2-methoxy-4(3H)-pyrimidinones 1-3 and applied to high yielding chemoselective N3 methylation, ethylation and benzylation reactions. Removal of the 2-methoxy group followed by a second alkylation affords unsymmetrically 1,3-disubstituted uracils.
