1006-24-2 Usage
General Description
3-Ethyl-6-methylpyrimidine-2,4(1H,3H)-dione, also known as ethylmethylpyrimidinedione, is a chemical compound with the molecular formula C7H10N2O2. It is a pyrimidine derivative and is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. 3-Ethyl-6-methylpyrimidine-2,4(1H,3H)-dione has the potential to act as a bronchodilator, anti-inflammatory, and anti-asthmatic agent. It has also been reported to possess anticonvulsant and analgesic activities, making it a promising candidate for the development of new therapeutic agents. Additionally, it has been studied for its potential as an antimicrobial and antifungal agent. Overall, 3-Ethyl-6-methylpyrimidine-2,4(1H,3H)-dione is an important chemical with diverse potential applications in the pharmaceutical and agricultural industries.
Check Digit Verification of cas no
The CAS Registry Mumber 1006-24-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,0,0 and 6 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1006-24:
(6*1)+(5*0)+(4*0)+(3*6)+(2*2)+(1*4)=32
32 % 10 = 2
So 1006-24-2 is a valid CAS Registry Number.
InChI:InChI=1/C7H10N2O2/c1-3-9-6(10)4-5(2)8-7(9)11/h4H,3H2,1-2H3,(H,8,11)
1006-24-2Relevant articles and documents
A diversity of alkylation/acylation products of uracil and its derivatives: Synthesis and a structural study
Michalak, Olga,Cmoch, Piotr,Krzeczyński, Piotr,Cybulski, Marcin,Le?, Andrzej
, p. 354 - 362 (2019/01/10)
tert-Butyl dicarbonate (Boc2O) and ethyl iodide (EtI) reactions with uracil (U), thymine (T) and 6-methyluracil (6-MU) were performed following routine procedures in pyridine/DMF solvents and with DMAP as the catalyst. Among 20 synthesized compounds, a derivative of 6-methyluracil substituted by the Boc-pyridine moiety at the C5 position appeared unexpectedly. The NMR spectra confirmed the molecular structure of all uracil derivatives. Parallel quantum mechanical DFT calculations supported the experimental findings.
HSAB driven chemoselectivity in alkylation of uracil derivatives. A high yielding preparation of 3-alkylated and unsymmetrically 1,3-dialkylated uracils
Gambacorta, Augusto,Farah, Mohamed Elmi,Tofani, Daniela
, p. 12615 - 12628 (2007/10/03)
A qualitative hardness scale (N134) has been found for the conjugated bases of 2-methoxy-4(3H)-pyrimidinones 1-3 and applied to high yielding chemoselective N3 methylation, ethylation and benzylation reactions. Removal of the 2-methoxy group followed by a second alkylation affords unsymmetrically 1,3-disubstituted uracils.
