100668-75-5

Upstream product

• 86232-53-3 3-Methyl-4,5-dimethoxyaniline 
• 4463-33-6 1,2-dimethoxy-3-methylbenzene 
• 78312-28-4 5-nitro-2,3-dimethoxytoluene 
• 80547-80-4 3,4-dimethoxy-5-methylbenzaldehyde 
• 32263-14-2 4-hydroxy-3-methoxy-5-methylbenzaldehyde 

Downstream Products

• 611-68-7 2-methoxy-6-methyl-1,4-benzoquinone 
• 38790-14-6 1,2,5-trimethoxy-3-methylbenzene 
• 100761-40-8 (+/-)-2-(1,5-dimethyl-4-hexenyl)-3-methoxy-5-methyl-2,5-cyclohexadiene-1,4-dione <(+/-)-O-methylperezone> 
• 100668-78-8 (+/-)-leucoperezone trimethyl ether 
• 100668-77-7 (+/-)-8-hydroxyleucoperezone 
• 1215006-53-3 3,4-dimethoxy-5-methylphenyl isopropylcarbamate 
• 1319714-04-9 1,2-dimethoxy-5-(methoxymethoxy)-3-methylbenzene 
• 1401427-20-0 C₄₂H₄₀O₁₁ 

Relevant academic research and scientific papers

METHODS FOR PREPARING BIS-TETRAHYDROISOQUINOLINE-CONTAINING COMPOUNDS

(-)-Jorumycin, ecteinascidin 743, saframycin A and related compounds, methods of preparing the same, formulations comprising the compounds, and methods of treating proliferative diseases with the same are provided.

Total syntheses of HMP-Y1, hibarimicinone, and HMP-P1

Total syntheses of HMP-Y1, atrop-HMP-Y1, hibarimicinone, atrop-hibarimicinone, and HMP-P1 are described using a two-directional synthesis strategy. A novel benzyl fluoride Michael-Claisen reaction sequence was developed to construct the complete carbon sk

Regioselective reactions of highly substituted arynes

"Chemical Equation Presented" The fully regioselective reactivity of four new highly substituted silyl aryl triflate aryne precursors in aryne acyl-alkylation, acyl-alkylation/ condensation, and heteroannulation reactions is reported. The application of these more complex arynes provides access to diverse natural product scaffolds and obviates late-stage functlonallzation of aromatic rings.

FORMAL TOTAL SYNTHESIS OF β-PIPITZOL

(+/-)-O-methylperezone (1b) was obtained by selective oxidative demethylation of (+/-)-leucoperezone trimethyl ether (4a).Compound (4a) was prepared by condensation of 2,3,5-trimethoxytoluene (5e) with 6-methyl-5-heptene-2-one, followed by reductive removal of the tertiary alcohol.The aromatic precursor 5e was prepared in four steps from 2,3-dimethoxytoluene (5a) and, alternatively, in three steps from 5-bromoveratraldehyde (6a).Racemic 1b and 4a were directly compared with the optically active molecules prepared from natural R(-)-perezone (1a).