100761-40-8 Usage
Description
(+/-)-2-(1,5-dimethyl-4-hexenyl)-3-methoxy-5-methyl-2,5-cyclohexadiene-1,4-dione, also known as (+/-)-O-methylperezone, is a cyclohexadiene-1,4-dione derivative with a molecular formula of C14H18O3 and a molecular weight of 234.29 g/mol. It is primarily used in the field of organic synthesis and is known for its potential biological and pharmacological activities. However, it is important to handle this chemical with caution as it may pose certain health and environmental hazards if not handled properly.
Uses
Used in Organic Synthesis:
(+/-)-2-(1,5-dimethyl-4-hexenyl)-3-methoxy-5-methyl-2,5-cyclohexadiene-1,4-dione <(+/-)-O-methylperezone> is used as a key intermediate in the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and other specialty chemicals. Its unique structure and reactivity make it a valuable building block for the development of new molecules with potential applications in various industries.
Used in Pharmaceutical Industry:
(+/-)-2-(1,5-dimethyl-4-hexenyl)-3-methoxy-5-methyl-2,5-cyclohexadiene-1,4-dione <(+/-)-O-methylperezone> is used as a starting material for the development of new drugs with potential therapeutic applications. Its biological and pharmacological activities are being investigated for the treatment of various diseases and conditions, making it a promising candidate for drug discovery and development.
Used in Agrochemical Industry:
(+/-)-2-(1,5-dimethyl-4-hexenyl)-3-methoxy-5-methyl-2,5-cyclohexadiene-1,4-dione <(+/-)-O-methylperezone> is used as a precursor for the synthesis of agrochemicals, such as pesticides and herbicides. Its unique chemical properties allow for the development of novel compounds with improved efficacy and selectivity, contributing to more sustainable agricultural practices.
Used in Specialty Chemicals Industry:
(+/-)-2-(1,5-dimethyl-4-hexenyl)-3-methoxy-5-methyl-2,5-cyclohexadiene-1,4-dione <(+/-)-O-methylperezone> is used as a raw material for the production of specialty chemicals, such as dyes, fragrances, and flavorings. Its versatile chemical structure enables the creation of new compounds with unique properties and applications, catering to the diverse needs of various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 100761-40-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,0,7,6 and 1 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 100761-40:
(8*1)+(7*0)+(6*0)+(5*7)+(4*6)+(3*1)+(2*4)+(1*0)=78
78 % 10 = 8
So 100761-40-8 is a valid CAS Registry Number.
100761-40-8Relevant articles and documents
Total Synthesis of (?)-Perezoperezone through an Intermolecular [5+2] Homodimerization of Hydroxy p-Quinone
Long, Yang,Ding, Yiming,Wu, Hai,Qu, Chunlei,Liang, Hong,Zhang, Min,Zhao, Xiaoli,Long, Xianwen,Wang, Shu,Puno, Pema-Tenzin,Deng, Jun
, p. 17552 - 17557 (2019/11/16)
The first copper-catalyzed intermolecular [5+2] homodimerization of hydroxy p-quinone is presented, furnishing bicyclo[3.2.1]octadienone core structures in typically good yields and excellent diastereoselectivities. Applying this synthetic approach enables a concise nine-step total synthesis of (?)-perezoperezone from commercially available 3,5-dimethoxytoluene.
Rearrangements of cyclobutenones. Synthesis of benzoquinones from 4-alkenyl-4-hydroxycyclobutenones
Perri, Steven T.,Moore, Harold W.
, p. 1897 - 1905 (2007/10/02)
The rearrangement of 4-alkenyl-4-hydroxycyclobutenones to quinones and related aromatic compounds is described. This rearrangement is complimentary to the previously reported ring expansions of 4-aryl- and 4-alkynyl-4-hydroxycyclobutenones. The synthetic scope and utility of the reaction are discussed. It is employed as a key step in the synthesis of a number of benzoquinones as well as in the total synthesis of the natural product, (±)-O-methylperezone and its regioisomer, (±)-O-methylisoperezone as well as coenzyme Q0 and aurantiogliocladin.
A SHORT AND EFFICIENT SYNTHESIS OF (+/-) O-METHYLPEREZONE BASED ON A NOVEL OXIDATIVE DEGRADATION APPROACH
Saa, Jose M.,Llobera, Antonia
, p. 5045 - 5046 (2007/10/02)
A short synthesis of (+/-) O-methylperezone based on a novel oxidative degradation approach (ODA) has been achieved.Distinguished features are : the direct metalation of a phenolic benzylamine and its oxidative degradation to the corresponding 1,4-benzoquinone by the action of Fermy's salt.
