10075-49-7Relevant articles and documents
Enantioselective synthesis of pyrroloindolines by a formal [3 + 2] cycloaddition reaction
Repka, Lindsay M.,Ni, Jane,Reisman, Sarah E.
, p. 14418 - 14420 (2010)
(R)-BINOL?SnCl4 was found to catalyze a formal [3 + 2] cycloaddition reaction between C(3)-substituted indoles and 2-amidoacrylates to provide pyrroloindolines. A variety of pyrroloindolines were prepared with high enantioselectivity in one step from simple precursors. This methodology is expected to facilitate the total synthesis of pyrroloindoline alkaloids, an important class of biologically active natural products.
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Noland,W.E.,Reich,C.
, p. 828 - 832 (1967)
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SELECTIVE INHIBITORS OF CLINICALLY IMPORTANT MUTANTS OF THE EGFR TYROSINE KINASE
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, (2019/01/21)
The present invention provides compounds of Formula (I) or a subgeneric structure or species thereof, or a pharmaceutically acceptable salt, ester, solvate, and/or prodrug thereof, and methods and compositions for treating or ameliorating abnormal cell pr
SUBSTITUTED QUINOXALINE DERIVATIVES
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Page/Page column 292, (2016/12/01)
The present invention relates to substituted quinoxaline derivatives. These compounds are useful for the prevention and/or treatment of several medical conditions including hyperproliferative disorders and diseases.