100858-20-6

Basic information

• Product Name: (22R)-des-A,B-8β-(benzoyloxy)-25-<(methoxymethyl)oxy>cholest-23-yn-22-ol
• Synonyms: (22R)-des-A,B-8β-(benzoyloxy)-25-<(methoxymethyl)oxy>cholest-23-yn-22-ol
• CAS NO: 100858-20-6
• Molecular Weight: 442.596
• Mol File: 100858-20-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (22R)-des-A,B-8β-(benzoyloxy)-25-<(methoxymethyl)oxy>cholest-23-yn-22-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (22R)-des-A,B-8β-(benzoyloxy)-25-<(methoxymethyl)oxy>cholest-23-yn-22-ol(100858-20-6)
• EPA Substance Registry System: (22R)-des-A,B-8β-(benzoyloxy)-25-<(methoxymethyl)oxy>cholest-23-yn-22-ol(100858-20-6)

Safety Data

• Hazardous Substances Data: 100858-20-6(Hazardous Substances Data)

Upstream product

• 98-88-4 benzoyl chloride 
• 100858-20-6 de-A,B-8β-(benzoyloxy)-25-<(methoxymethyl)oxy>cholest-23-yn-22-ol 
• 145354-33-2 (22R)-des-A,B-8β-(benzoyloxy)-22<<(1'R)-2'-carboxy-1'-methylethyl>oxy>-23-cholestyn-25-ol 
• 145354-29-6 (20S)-des-A,B-8β-(benzoyloxy)-20-<(2'R,6'R)-6'-methyl-4'-oxo-1',3'-dioxan-2'-yl>pregnane 
• 55812-82-3 (1R,3aR,4S,7aR)-7a-methyl-1-<(2E)-(1R,4R)-1,4,5-trimethyl-hex-2-enyl>-octahydro-1H-inden-4-ol 
• 68702-86-3 (24R,22E)-des-A,B-8β-(benzoyloxy)ergost-22-ene 
• 66774-71-8 Benzoic acid (1R,3aR,4S,7aR)-7a-methyl-1-((S)-1-methyl-2-oxo-ethyl)-octahydro-inden-4-yl ester 
• 145354-35-4 (22R)-des-A,B-8β-(benzoyloxy)-25-<(methoxymethyl)oxy>-22-<<(1'R)-3'-oxo-3'-<(methoxymethyl)oxy>-1'-methylpropyl>-oxy>cholest-23-yne 
• 100858-21-7 de-A,B-8β-(benzoyloxy)-25-<(methoxymethyl)oxy>cholest-23-yn-22-one 
• 115527-18-9 Benzoic acid (1R,3aR,7aR)-1-[(1S,2R)-5-hydroxy-2-((1R,3R)-3-hydroxy-1-methyl-butoxy)-1,5-dimethyl-hex-3-ynyl]-7a-methyl-octahydro-inden-4-yl ester 
• 115527-14-5 Benzoic acid (1R,3aR,7aR)-1-[(S)-1-((4R,6R)-4,6-dimethyl-[1,3]dioxan-2-yl)-ethyl]-7a-methyl-octahydro-inden-4-yl ester 
• 66774-71-8 Benzoic acid (1R,3aR,7aR)-7a-methyl-1-((S)-1-methyl-2-oxo-ethyl)-octahydro-inden-4-yl ester 
• 115527-19-0 Benzoic acid (1R,3aR,7aR)-1-[(1S,2R)-5-hydroxy-1,5-dimethyl-2-((R)-1-methyl-3-oxo-butoxy)-hex-3-ynyl]-7a-methyl-octahydro-inden-4-yl ester 
• 68702-86-3 Benzoic acid (1R,3aR,7aR)-7a-methyl-1-((E)-(1R,4R)-1,4,5-trimethyl-hex-2-enyl)-octahydro-inden-4-yl ester 

Downstream Products

• 21343-40-8 ercalcidiol 
• 100858-26-2 (22E,24S)-de-A,B-25-<(methoxymethyl)oxy>ergost-22-en-8-one 
• 100858-28-4 25-<(methoxymethyl)oxy>vitamin D2 tert-butyldimethylsilyl ether 
• 100858-24-0 (22E,24S)-de-A,B-8β-(benzoyloxy)-25-<(methoxymethyl)oxy>ergost-22-ene 
• 100937-72-2 (22E,24R)-de-A,B-8β-(benzoyloxy)-25-<(methoxymethyl)oxy>ergost-22-ene 
• 100937-69-7 (22S)-de-A,B-8β-(benzoyloxy)-25-<(methoxymethyl)oxy>cholest-23-yn-22-ol 
• 100858-23-9 (22R,23Z)-de-A,B-8β-(benzoyloxy)-25-<(methoxymethyl)oxy>-22-<(phenylcarbamoyl)oxy>cholest-23-ene 
• 100937-71-1 (22S,23Z)-de-A,B-8β-(benzoyloxy)-25-<(methoxymethyl)oxy>-22-<(phenylcarbamoyl)oxy>cholest-23-ene 
• 145354-39-8 1α-[(tert-butyldimethylsilyl)oxy]-25-[(methoxymethyl)oxy]previtamin D₂ tert-butyldimethylsilyl ether 
• 60133-18-8 ercalcitriol 
• 100937-70-0 (22S,23Z)-de-A,B-8β-(benzoyloxy)-25-<(methoxymethyl)oxy>cholest-23-en-ol 
• 100858-22-8 (22R,23Z)-de-A,B-8β-(benzoyloxy)-25-<(methoxymethyl)oxy>cholest-23-en-ol 
• 100858-21-7 de-A,B-8β-(benzoyloxy)-25-<(methoxymethyl)oxy>cholest-23-yn-22-one 
• 115527-21-4 Benzoic acid (1R,3aR,7aR)-1-((Z)-(1S,2S)-2-carbamoyloxy-5-methoxymethoxy-1,5-dimethyl-hex-3-enyl)-7a-methyl-octahydro-inden-4-yl ester 

Relevant articles and documents

Studies on the opening of dioxanone and acetal templates and application to the synthesis of 1α,25-dihydroxyvitamin D2

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Studies on the Synthesis of Side-Chain Hydroxylated Metabolites of Vitamin D. 2. Stereocontrolled Synthesis of 25-Hydroxyvitamin D2

An efficient synthesis of 25-hydroxyvitamin D2 is described.The chiral center at C-24 was introduced by the stereospecific and regioselective displacement of an allylic carbamate by a cuprate.The triene system was assembled by Horner-Wittig coupling of ke