100865-80-3

Upstream product

• 6325-06-0 3,3-Bis(4-chlorphenyl)-2-butanon 
• 405551-72-6 2,2-bis-(4-chloro-phenyl)-propionic acid methyl ester 
• 83-05-6 bis(4'-chlorophenyl)acetic acid 
• 30738-51-3 ethyl 2,2-bis(4-chlorophenyl)acetate 
• 74-88-4 methyl iodide 
• 21985-98-8 2,3-bis-(4-chloro-phenyl)-butane-2,3-diol 
• 64-18-6 formic acid 
• 80-06-8 chlorfenethol 
• 127-17-3 2-oxo-propionic acid 
• 108-90-7 chlorobenzene 

Downstream Products

• 1035261-68-7 diethyl 2-(2,2-bis(4-chlorophenyl)propanoyl)-malonate 
• 1040860-75-0 C₁₅H₁₁Cl₃O 

Relevant academic research and scientific papers

Pd(II)-catalyzed enantioselective C-H olefination of diphenylacetic acids

(Chemical Equation Presented) Pd(II)-catalyzed enantioselective C-H olefination of diphenylacetic acid substrates has been achieved through the use of monoprotected chiral amino acid ligands. The absolute configuration of the resulting olefinated products

PHARMACEUTICAL COMBINATIONS COMPRISING PYRAZOLE DERIVATIVES AS PROTEIN KINASE MODULATORS

The invention provides a combination comprising an ancillary compound (e.g. one, two or more ancillary compounds) and a compound of the formula (I) having protein kinase B inhibiting activity: wherein A is a saturated hydrocarbon linker group containing f

NAPHTHALENONE COMPOUNDS EXHIBITING PROLYL HYDROXYLASE INHIBITORY ACTIVITY, COMPOSITIONS, AND USES THEREOF

Compounds of Formula (I) and Formula (II) are useful as inhibitors of HIF prolyl hydroxylases. Compounds of Formula(I) and Formula (II) have the following structures, where the definitions of the variables are provided herein.

PHARMACEUTICAL COMPOUNDS

The invention provides compounds of the formula (I) having ROCK kinase and/or protein kinase p70S6K inhibiting activity: wherein A is a saturated hydrocarbon linker group containing from 1 to 7 carbon atoms, the linker group having a maximum chain length

Substituted imidazoles as dual histamine H1 and H3 agonists or antagonists

The present invention discloses novel substituted imidazole compounds which have either or dual histamine-H1 and H3 receptor antagonist activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such imidazoles as well as methods of using them to treat allergy, inflammatory and CNS-related diseases and others.

CARBOXYLATION OF ALCOHOLS WITH CARBON MONOXIDE SUPERSATURATED IN STRONG ACID. FACILE SYNTHESIS OF 2,2-BIS(4-HALOPHENYL)ACETIC, -PROPIONIC, AND RELATED ACIDS

Using 97percent H2SO4 supersaturated with carbon monoxide, bis(4-halophenyl)methanols, 1,1-bis(4-halophenyl)ethanols and related alcohols were transformed to the carboxylic acids in 60-95percent yields.