100960-68-7 Usage
General Description
4-chloro-2-methoxybenzonitrile is a chemical compound with the formula C8H6ClNO. It is a white to off-white crystalline powder that is used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. 4-chloro-2-methoxybenzonitrile is a nitrile, which means it contains a carbon triple-bonded to a nitrogen atom. Its specific properties and reactivity make it useful in various chemical reactions, including the synthesis of complex organic molecules. Additionally, 4-chloro-2-methoxybenzonitrile may have potential applications in the field of medicinal chemistry due to its structural features and potential biological activity. Proper handling and storage of this chemical are important to ensure the safety of workers and the environment.
Check Digit Verification of cas no
The CAS Registry Mumber 100960-68-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,0,9,6 and 0 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 100960-68:
(8*1)+(7*0)+(6*0)+(5*9)+(4*6)+(3*0)+(2*6)+(1*8)=97
97 % 10 = 7
So 100960-68-7 is a valid CAS Registry Number.
100960-68-7Relevant articles and documents
Ligand-Promoted Non-Directed C?H Cyanation of Arenes
Liu, Luo-Yan,Yeung, Kap-Sun,Yu, Jin-Quan
supporting information, p. 2199 - 2202 (2019/01/24)
This article reports the first example of a 2-pyridone accelerated non-directed C?H cyanation with an arene as the limiting reagent. This protocol is compatible with a broad scope of arenes, including advanced intermediates, drug molecules, and natural products. A kinetic isotope experiment (kH/kD=4.40) indicates that the C?H bond cleavage is the rate-limiting step. Also, the reaction is readily scalable, further showcasing the synthetic utility of this method.
HETEROCYCLIC KINASE INHIBITORS
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Page 81, (2010/02/08)
Compounds having the formula (I) are useful for inhibiting protein kinases. Also disclosed are methods of making the compounds, compositions containing the compounds, and methods of treatment using the compounds.