101017-54-3

Usage

Uses

Used in Pharmaceutical Industry:
(3Z)-3-[(4-methoxyphenyl)methylidene]-2,3-dihydro-4H-thiochromen-4-one is used as a pharmaceutical candidate for its potential biological activities. Its unique structural arrangement and potential medicinal properties make it a promising compound for further research and development in the pharmaceutical industry.
Used in Medicinal Chemistry Research:
(3Z)-3-[(4-methoxyphenyl)methylidene]-2,3-dihydro-4H-thiochromen-4-one is used as a subject of medicinal chemistry research to explore its potential pharmaceutical applications. (3Z)-3-[(4-methoxyphenyl)methylidene]-2,3-dihydro-4H-thiochromen-4-one's unique structure and potential biological activities make it an interesting area of study for researchers in the field of medicinal chemistry.

Upstream product

• 3528-17-4 2,3-dihydro-4H-[1]benzothiopyran-4-one 
• 123-11-5 4-methoxy-benzaldehyde 

Downstream Products

• 130689-12-2 3-(4'-methoxybenzylidene)thiochroman-4-one-1-oxide 
• 130689-13-3 3-(4'-methoxybenzylidene)thiochroman-4-one-1,1-dioxide 
• 137985-64-9 4-(4-methoxyphenyl)-3,4-dihydro-1H-thiochromeno[4,3-d]pyrimidine-2(5H)-thione 
• 1373520-33-2 (2R,3S,3aR)-tert-butyl 3-(4-methoxyphenyl)-2,3,3a,4-tetrahydrothiochromeno[4,3-b]pyrrole-2-carboxylate 
• 135521-76-5 1-amino-4-(4-methoxyphenyl)-4H,5H-<1>benzothiopyrano<4,3-b>pyran-3-carbonitrile-6-sulfone 
• 115091-77-5 2-amino-4-(4-methoxyphenyl)-4H,5H-<1>benzothiopyrano<4,3-b>pyran-3-carbonitrile 
• 115091-86-6 3-Methoxy-1-(4-methoxy-phenyl)-10H-9-thia-4-aza-phenanthrene-2-carbonitrile 

Relevant academic research and scientific papers

A mild and efficient stereoselective synthesis of (Z)- and (E)-allyl sulfides and potent antifungal agent, (Z)-3-(4-methoxybenzylidene)thiochroman-4- one from Morita-Baylis-Hillman acetates

A facile stereoselective synthesis of (Z)- and (E)-allyl sulfides has been accomplished from Morita-Baylis-Hillman acetates in one-pot by treatment with benzene thiol in the presence of catalytic amounts of 15% aqueous NaOH and TBAI in DMSO at room temper

Green chemistry preparation of MgO nanopowders: efficient catalyst for the synthesis of thiochromeno[4,3-b]pyran and thiopyrano[4,3-b]pyran derivatives

A mild and efficient method for the synthesis of thiochro meno[4,3-b]pyran and thiopyrano[4,3-b]pyran derivatives using MgO nanopowders as a catalyst is described. The MgO nanopowders were prepared via a green biosynthesis method using an extract of Rosma

Structural studies of seven homoisoflavonoids, six thiohomoisoflavonoids, and four structurally related compounds

1H and 13C NMR chemical shifts have been determined and assigned based on PFG 1H, 13C HM...C, and HMBC experiments for 3-(4'-X-benzyl)-4-chromenones (Ia, X = CN and Ib, X = NO 2), 3-(4'-X-benzyl)-4-th

Synthesis of novel tricyclic heterocyclic compounds as potential anticancer agents using chromanone and thiochromanone as synthons

The arylmethylene of benzopyrane or benzothiopyrane 3,4 have been synthesized and condensed with hydrazine, guanidine and thiourea to yield pyrazole 5-8, aminopyrimidine 9,10 and thioxopyrimidine derivatives 11,12, respectively. Compounds 3 or 4 on treatment with malononitrile in the presence of ammonium acetate/acetic acid or in the presence of piperidine/ methanol to yield benzopyrano- and benzothiopyranopyridine 13,14 and benzopyrano- and benzothiopyrane 15,16, respectively. The oxirane of compound 3 is prepared and condensed with CS2 to yield the tricyclic system, thioxothienobenzopyrane 21. Ylidenemalononitrile for the ketone 1 and 2 are synthesized and condensed with aromatic aldehyde in presence of ammonium acetate/acetic acid to yield benzopyranopyridine and benzothiopyranopyridine derivatives 24,25, respectively, which are the isomer of compounds 13,14. Ylidenemalononitrile on condensation with phenylisothiocyanate yields benzo-pyrano- and benzothiopyranothioxopyridine 28,29, respectively.

Reactivity of α-arylidene benzoheteracyclanone dibromides toward azide ion: An effective approach to 3-(α-substituted-benzyl)chromones and -1-thiochromones

Treatment of dibromides of 3-arylidenechromanones and -1-thiochromanones with sodium azide resulted in the formation of 3-(α-azidobenzyl)chromones and -1-thiochromones whereas dibromides having no antiperiplanar vicinal hydrogen in the ring such as flavanone, 1-thioflavanone and benzosuberone derivatives afforded only the parent enones by bromine elimination. Evidence supported the intermediacy of 3-(α-bromobenzyl)chromones and -1-thiochromones in this reaction. These postulated intermediates were prepared in an independent way and transformed into azides in high yield.