1011269-13-8

Basic information

• Product Name: N-phenyl-N-phenylethynylcarbamic acid tert-butyl ester
• Synonyms: N-phenyl-N-phenylethynylcarbamic acid tert-butyl ester
• CAS NO: 1011269-13-8
• Molecular Weight: 293.365
• Mol File: 1011269-13-8.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: N-phenyl-N-phenylethynylcarbamic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-phenyl-N-phenylethynylcarbamic acid tert-butyl ester(1011269-13-8)
• EPA Substance Registry System: N-phenyl-N-phenylethynylcarbamic acid tert-butyl ester(1011269-13-8)

Safety Data

• Hazardous Substances Data: 1011269-13-8(Hazardous Substances Data)

Upstream product

• 3422-01-3 tert-butyl phenylcarbamate 
• 536-74-3 phenylacetylene 
• 24424-99-5 di-tert-butyl dicarbonate 
• 142-04-1 aniline hydrochloride 
• 698-88-4 (2,2-dichlorovinyl)benzene 
• 932-87-6 1-Bromo-2-phenylacetylene 

Downstream Products

• 35746-43-1 3-phenyl-5-phenyloxazol-2(3H)-one 
• 6652-42-2 2-Oxo-3,4,5-triphenyl-2,3-dihydro-oxazol 
• 17767-81-6 3,5-diphenyloxazolidine-2,4-dione 
• 621-06-7 2,N-diphenylacetamide 
• 4732-66-5 2-oxo-N,2-diphenylacetamide 
• 1383533-44-5 C₁₈H₁₅NO₂ 

Relevant articles and documents

Catalyst-Free [4+2] Cycloaddition of Ynamides with 2-Halomethyl Phenols to Construct 2-Amino-4 H-Chromenes and α-Halo Enamides Simultaneously

We report the development of a facile protocol for the [4+2] cycloaddition of ynamides and 2-halomethyl phenols to afford the corresponding 2-amino-4H-chromenes and α-halo enamides under catalyst-free conditions. The reaction proceeds under mild condition

A Unified Approach for Divergent Synthesis of Heterocycles via TMSOTf-Catalyzed Formal [3+2] Cycloaddition of Electron-Rich Alkynes

We present a synthetic protocol for the construction of polysubstituted five-membered heterocycles via TMSOTf-catalyzed formal [3+2] cycloaddition of electron-rich alkynes, which features free from any metal, atom economy and water as the main by-product. Furthermore, alkenyl ether adduct has been verified as the key intermediate. Notably, by utilizing this approach, we can synthesize a broad range of polysubstituted furans, thiophenes and pyrroles, and extend this transformation to deliver fused-polyheterocycles. This reaction can be achieved on a gram scale and the corresponding products are intermediates for producing diverse potentially useful scaffolds. (Figure presented.).

Metal-free hydration of ynamides: Convenient approach to amides

The trifluoroacetic acid (TFA) mediated hydration of ynamides was developed, which is an efficient approach for the synthesis of N-monosubstituted amides. This convenient method is effective with a wide range of substrates under room temperature condition, and the products are obtained in high to excellent yields through an easy work-up process.