799804-49-2

Basic information

• Product Name: Benzeneacetic acid, 2-[(trimethylsilyl)ethynyl]-, methyl ester
• CAS NO: 799804-49-2
• Molecular Formula: C14H18O2Si
• Molecular Weight: 246.381
• Mol File: 799804-49-2.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Benzeneacetic acid, 2-[(trimethylsilyl)ethynyl]-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneacetic acid, 2-[(trimethylsilyl)ethynyl]-, methyl ester(799804-49-2)
• EPA Substance Registry System: Benzeneacetic acid, 2-[(trimethylsilyl)ethynyl]-, methyl ester(799804-49-2)

Safety Data

• Hazardous Substances Data: 799804-49-2(Hazardous Substances Data)

Upstream product

• 66370-75-0 methyl (2-iodophenyl)acetate 
• 1066-54-2 trimethylsilylacetylene 
• 40400-15-5 2-(2-iodophenyl)acetonitrile 
• 59473-45-9 2-(chloromethyl)iodobenzene 
• 103-82-2 phenylacetic acid 

Downstream Products

• 637348-19-7 (2-ethynylphenyl)acetic acid methyl ester 
• 952594-46-6 methyl 2-(2-((3-fluorophenyl)ethynyl)phenyl)acetate 
• 952594-56-8 2-(2-((3-fluorophenyl)ethynyl)phenyl)acetic acid 
• 952594-48-8 methyl 2-(2-((2-ethyl-6-methylphenyl)ethynyl)phenyl)acetate 
• 952594-49-9 methyl 2-(2-(o-tolylethynyl)phenyl)acetate 
• 952594-59-1 2-(2-(o-tolylethynyl)phenyl)acetic acid 
• 936693-17-3 2-(2-ethynylphenyl)acetic acid 
• 952594-44-4 methyl 2-[2-(2-phenylethynyl)phenyl]acetate 
• 952594-54-6 2-(2-(phenylethynyl)phenyl)acetic acid 
• 952594-45-5 methyl 2-{2-[2-(4-methoxyphenyl)ethynyl]phenyl}acetate 
• 952594-55-7 2-(2-((4-methoxyphenyl)ethynyl)phenyl)acetic acid 
• 16535-88-9 (2-acetyk-phenyl)-acetic acid methyl ester 
• 29427-70-1 methyl 3-oxo-2,3-dihydro-1H-indene-1-carboxylate 
• 799804-36-7 methyl 2-(2-{2-[(methylsulfonyloxy)oxy]acetyl}phenyl)acetate 

Relevant articles and documents

Gold-catalyzed intermolecular [4+1] spiroannulation: via site-selective aromatic C(sp2)-H functionalization and dearomatization of phenol derivatives

Herein, we have developed a novel and simple protocol to realize the C-H bond functionalization/dearomatization of naphthols and phenols with ortho-alkynylaryl-α-diazoesters under gold(i) catalysis. In this protocol, various spirocyclic molecules could be obtained in good yields with excellent chemo- and regio-selectivity and moderate to good diastereoselectivity. This journal is

FAK AND FLT3 INHIBITORS

The use of a compound of the formula (I): (Formula (I)) in the preparation of a medicament for treating Acute Myeloid Leukemia or a disease ameliorated by the inhibition of Flt3, or Flt3 and FAK.

6-exo versus 7-endo iodolactonizations of 2-(alkynyl)phenylacetic acids

Exposure of 2-alkynylphenylacetic acids to excess iodine in acetonitrile containing anhydrous potassium carbonate delivers good yields, either of the corresponding isochroman-3-ones or benzo[d]oxepin-2(1H)-ones, depending upon the alkyne substituent: when