10128-92-4

Basic information

• Product Name: 3-Pyridinecarboxamide,1,2-dihydro-2-oxo-(9CI)
• Synonyms: 3-Pyridinecarboxamide,1,2-dihydro-2-oxo-(9CI);3-Pyridinecarboxamide, 1,2-dihydro-2-oxo-
• CAS NO: 10128-92-4
• Molecular Formula: C₆H₆N₂O₂
• Molecular Weight: 138.124
• Product Categories: AMIDE
• Mol File: 10128-92-4.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 528.7 °C at 760 mmHg
• Flash Point: 273.6 °C
• Appearance: /
• Density: 1.354 g/cm³
• Vapor Pressure: 2.89E-11mmHg at 25°C
• Refractive Index: 1.578
• CAS DataBase Reference: 3-Pyridinecarboxamide,1,2-dihydro-2-oxo-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Pyridinecarboxamide,1,2-dihydro-2-oxo-(9CI)(10128-92-4)
• EPA Substance Registry System: 3-Pyridinecarboxamide,1,2-dihydro-2-oxo-(9CI)(10128-92-4)

Safety Data

• Hazardous Substances Data: 10128-92-4(Hazardous Substances Data)

Usage

Uses

2-Hydroxynicotinamide has tuberculostatic activity.

InChI:InChI=1/C6H6N2O2/c7-5(9)4-2-1-3-8-6(4)10/h1-3H,(H2,7,9)(H,8,10)

Upstream product

• 364-22-7 2-fluoronicotinamide 
• 609-71-2 1,2-dihydro-2-oxonicotinic acid 
• 27805-12-5 ethyl-2-oxo-1,2-dihydro-3-pyridinecarbonitrile 
• 101392-31-8 N-acetyl-2-hydroxynicotinamide 
• 10366-35-5 2-chloronicotinamide 
• 110-89-4 piperidine 
• 20577-27-9 2-hydroxy-3-cyanopyridine 

Downstream Products

• 609-71-2 2-hydroxy-3-carboxypyridine 
• 31309-08-7 2-chloro-5-nitropyridine-3-carbonitrile 
• 60524-15-4 2-chloro-5-nitronicotinamide 
• 135795-55-0 2-chloro-3-chlorocarbonyl-5-nitropyridine 
• 379268-25-4 C₃₂H₂₆N₂O₉ 

Relevant articles and documents

Synthesis of certain 1-β-D-ribofuranosyl-1,2-dihydro-2- oxopyridines structurally related to nicotinamide ribonucleoside

-

Direct Conversion of Haloarenes to Phenols under Mild, Transition-Metal-Free Conditions

A high-yielding and practical method for the synthesis of phenols from electron-deficient haloarenes and heteroarenes has been developed. The products are formed from acetohydroxamic acid as the hydroxide source via a novel SNAr reaction/Lossen rearrangement sequence. Notably, these reactions employ inexpensive and air-stable reagents, require no special handling, occur under mildly basic conditions, and form products in high yields in the presence of electrophilic and protic functionality. The utility of this methodology is demonstrated by the high-yielding hydroxylation of two base-sensitive complex substrates.

The deoxydative substitution reactions of nicotinamide and nicotinic acid N-oxides by 1-adamantanethiol in acetic anhydride

-