1013031-65-6

Basic information

• Product Name: (2,6-DibroMophenyl)Methanol
• Synonyms: (2,6-DibroMophenyl)Methanol;2,6-Dibromobenzyl alcohol
• CAS NO: 1013031-65-6
• Molecular Formula: C₇H₆Br₂O
• Molecular Weight: 265.92994
• Mol File: 1013031-65-6.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 316.5±27.0 °C(Predicted)
• Appearance: /
• Density: 1.960±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 13.53±0.10(Predicted)
• CAS DataBase Reference: (2,6-DibroMophenyl)Methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (2,6-DibroMophenyl)Methanol(1013031-65-6)
• EPA Substance Registry System: (2,6-DibroMophenyl)Methanol(1013031-65-6)

Safety Data

• Hazardous Substances Data: 1013031-65-6(Hazardous Substances Data)

Usage

General Description

(2,6-Dibromophenyl)methanol, also known as 2,6-bis(bromomethyl)phenol, is a chemical compound known for its use in the field of organic synthesis. (2,6-DibroMophenyl)Methanol contains bromine, and its systematic name from IUPAC is 2,6-dibromo-benzyl alcohol. It generally appears as off-white crystals and has significant applications in pharmaceuticals or as an intermediate in organic reactions. However, details of its physiological and toxicological impacts on the environment and human health are not extensively studied, thus handling and usage should be made with care in controlled environments. Like other chemicals, it must be used responsibly, taking into account the necessary safety measures.

Upstream product

• 108-36-1 1,3-dibromobenzene 
• 67713-23-9 2,6-dibromobenzaldehyde 
• 93701-32-7 2,6-dibromobenzyl bromide 
• 858006-31-2 1,3-dibromo-2-(chloromethyl)benzene 

Downstream Products

• 601-84-3 2,6-dibromobenzoic acid 
• 858006-31-2 1,3-dibromo-2-(chloromethyl)benzene 
• 1013031-66-7 2,6-dibromobenzyl methoxymethyl ether 
• 863870-92-2 4-bromo-2-phenylbenzo[b]furan 
• 1202570-33-9 ethyl (2S)-2-{[[(2,6-dibromobenzyl)oxy](diisopropyl)silyl]oxy}-propanoate 

Relevant articles and documents

Preparation process 2-6 - dibromobenzoyl chloride

The invention discloses a preparation process for 2,6-dibromobenzene methylsulfonyl chloride. The preparation process comprises the following steps: with m-dibromobenzene as a starting raw material, subjecting the m-dibromobenzene to a five-step reaction of acylation, reduction, chlorine substitution, substitution and sulfonyl chlorination so as to obtain a target compound namely the 2,6-dibromobenzene methylsulfonyl chloride. The process provided by the invention uses cheap and easily-available raw materials, has good safety by using NCS to replace chlorine gas as a chlorinating agent, and facilitates practical application.

Mono- and Di-Mesoionic Carbene-Boranes: Synthesis, Structures and Utility as Reducing Agents

Mesoionic carbenes (MIC) of the 1,2,3-triazol-5-ylidene type are currently popular ligands in organometallic chemistry. Their use in main group chemistry has been rather limited. In this contribution we present mono- and di-MIC-boranes with MICs based on triazolylidenes. The synthesis involves in-situ deprotonation of the corresponding triazolium salts and their reaction with boranes to form the desired compounds. Whereas this reaction route worked well for all triazolium salts derived from the 1,4-regioisomer of the triazoles, for the methlyene-bridged bi-triazolium salt derived from a 1,5-substiuted triazole, we observed the unexpected decomposition of the bi-triazolium and the formation of a triazole-borane with a new N?B bond. All compounds were characterized via multinuclear NMR spectroscopy, mass spectrometry, and single crystal X-ray diffraction. Furthermore, the MIC-boranes were used as reducing agents for the reduction of the C=O of aldehydes to the corresponding alcohols.

Chiral Sulfide Catalysis for Desymmetrizing Enantioselective Chlorination

An unprecendented chiral sulfide catalyzed desymmetrizing enantioselective chlorination is disclosed. Various aryl-tethered diolefins and diaryl-tethered olefins afforded teralins and tricyclic hexahydrophenalene derivatives, respectively, bearing multiple stereogenic centers in high yields with excellent enantio- and diastereoselectivities. In contrast, the tertiary amine catalyst (DHQD)2PHAL led to a diastereomeric product. The products could be transformed into a variety of compounds, such as spiro-N-heterocycles.