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10137-87-8

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10137-87-8 Usage

Description

N-Ethyl-α-methylbenzenemethanamine, also known as N,α-diethylphenylethylamine, is a psychoactive chemical compound with the molecular formula C12H19N. It is a substituted phenethylamine and a derivative of amphetamine, bearing structural similarities to methamphetamine. N-Ethyl-α-methylbenzenemethanamine acts as a central nervous system stimulant and is classified as a psychoactive substance.

Uses

Used in Pharmaceutical Industry:
N-Ethyl-α-methylbenzenemethanamine is used as an active pharmaceutical ingredient for the development of stimulant medications due to its ability to stimulate the central nervous system.
Used in Research and Development:
It is utilized in scientific research as a reference compound for studying the effects of central nervous system stimulants and their potential applications in medicine.
Used in Illicit Drug Production:
Regrettably, N-Ethyl-α-methylbenzenemethanamine is also used in the illicit production of designer drugs, contributing to its classification as a substance with potential for abuse.
Due to its potential for misuse and abuse, the use and distribution of N-Ethyl-α-methylbenzenethanamine are restricted and regulated in many countries to prevent harmful effects on individuals and society.

Check Digit Verification of cas no

The CAS Registry Mumber 10137-87-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,1,3 and 7 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 10137-87:
(7*1)+(6*0)+(5*1)+(4*3)+(3*7)+(2*8)+(1*7)=68
68 % 10 = 8
So 10137-87-8 is a valid CAS Registry Number.
InChI:InChI=1/C10H15N/c1-3-11-9(2)10-7-5-4-6-8-10/h4-9,11H,3H2,1-2H3

10137-87-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name N-ethyl-1-phenylethanamine

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:10137-87-8 SDS

10137-87-8Relevant articles and documents

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Cunanan,Swan

, p. 2311 (1967)

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Disulfonimide-Catalyzed Asymmetric Reduction of N-Alkyl Imines

Wakchaure, Vijay N.,Kaib, Philip S. J.,Leutzsch, Markus,List, Benjamin

supporting information, p. 11852 - 11856 (2015/10/05)

A chiral disulfonimide (DSI)-catalyzed asymmetric reduction of N-alkyl imines with Hantzsch esters as a hydrogen source in the presence of Boc2O has been developed. The reaction delivers Boc-protected N-alkyl amines with excellent yields and enantioselectivity. The method tolerates a large variety of alkyl amines, thus illustrating potential for a general reductive cross-coupling of ketones with diverse amines, and it was applied in the synthesis of the pharmaceuticals (S)-Rivastigmine, NPS R-568 Hydrochloride, and (R)-Fendiline. A chiral disulfonimide (DSI)-catalyzed asymmetric reduction of N-alkyl imines with Hantzsch esters as a hydrogen source in the presence of Boc2O was developed. The reaction delivers Boc-protected N-alkyl amines with excellent yields and enantioselectivity. The method was successfully applied to the synthesis of the pharmaceuticals (S)-Rivastigmine, NPS R-568 Hydrochloride, and (R)-Fendiline.

ASYMMETRIC IMINE HYDROGENATION PROCESSES

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Page/Page column 28, (2008/06/13)

A process for the catalytic hydrogenation or asymmetric hydrogenation of imines of Formula (I) to the corresponding amines of Formula (II) is provided in which R1 is aryl ; R2 is aryl, cyclic, alkyl, alkenyl or alkynyl; and R3 is alky l. The catalytic system includes a ruthenium complex containing (1) a diamine and (2) a diphosphine or two monodentate phosphines ligands. Such process also relates to the asymmetric hydrogenation of prochiral imines to the chiral amines using chiral ruthenium complexes bearing chiral diphosphines or chiral monodentate phosphines and chiral diamines.

Saponification agents. 2. Synthesis of arylisocyanates with ethyl lactate and their use in racemic bases saponification

Brown,Moudachirou

, p. 10309 - 10320 (2007/10/02)

Reaction of the arylisocyanates 2a-c with ethyl (S)-(-)-lactate, followed by careful saponification, afforded the corresponding chiral acids (S)-(-)- 4a-c. The latter were successfully used for the resolution of various racemic bases belonging to both the ephedrine and α-aryl ethylamine series.

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