10156-38-4

Basic information

• Product Name: 1,3-Propanedione, 2-iodo-1,3-diphenyl-
• CAS NO: 10156-38-4
• Molecular Formula: C15H11IO2
• Molecular Weight: 350.156
• Mol File: 10156-38-4.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: 1,3-Propanedione, 2-iodo-1,3-diphenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Propanedione, 2-iodo-1,3-diphenyl-(10156-38-4)
• EPA Substance Registry System: 1,3-Propanedione, 2-iodo-1,3-diphenyl-(10156-38-4)

Safety Data

• Hazardous Substances Data: 10156-38-4(Hazardous Substances Data)

Usage

Derivative of

1,3-propanedione

Contains

an iodine atom and two phenyl groups

Common use

building block in the synthesis of various organic compounds and pharmaceuticals

Utilized as

a reagent in organic chemistry reactions

Specific reactions

formation of carbon-carbon and carbon-heteroatom bonds

Potential applications

medicinal chemistry and drug discovery

Structural features

contributes to its reactivity and potential in drug discovery

Safety precautions

handle with caution due to potential health and safety hazards

Upstream product

• 728-84-7 2-bromo-1,3-diphenylpropane-1,3-dione 
• 120-46-7 1,3-diphenylpropanedione 

Downstream Products

• 7553-56-2 iodine 
• 120-46-7 1,3-diphenylpropanedione 
• 65-85-0 benzoic acid 
• 29574-75-2 2,2-dihydroxy-1,3-diphenylpropan-1,3-dione 
• 1422036-62-1 1,3-diphenyl-2-((2,2,6,6-tetramethylpiperidin-1-yl)oxy)propane-1,3-dione 

Relevant articles and documents

Iodination of enol acetates and 1,3-diones using N-iodosaccharin

Iodination of enol acetates and 1,3-diones with N-iodosaccharin yielding the corresponding α-iodoketones and 2-iodo-1,3-diones is presented. Reactions are carried out at room temperature under neutral conditions and in short reaction times.

I2-Promoted [3+2] Cyclization of 1,3-Diketones with Potassium Thiocyanate: a Route to Thiazol-2(3H)-One Derivatives

An I2-promoted strategy has been developed for the synthesis of thiazol-2(3H)-one derivatives from 1,3-diketones with potassium thiocyanate. This [3+2] cyclization reaction involves C?S and C?N bond formation and exhibits good functional group tolerance. A series of thiazol-2(3H)-one derivatives are obtained in moderate to good yields. (Figure presented.).

Preparation method for 2-halogenated-1,3-dicarbonyl derivative

The invention discloses a preparation method for a 2-halogenated-1,3-dicarbonyl derivative. The preparation method is suitable for wide 1,3-dicarbonyl derivatives. The raw materials are easy to obtain, and multiple varieties are achieved. The product obtained through the method is diversified in type, and can be directly used and used for other further reactions. According to the method, reaction conditions are gentle, the reaction operation and after-treatment process is simple, reaction time is short, the yield is high, pollution is low, and the preparation method is suitable for industrial production.