101697-26-1

Basic information

• Product Name: 2‐[2‐bromo‐5‐tert‐butyl‐3‐(1,1,1,3,3,3‐hexafluoro‐2‐hydroxypropan‐2‐yl)phenyl]‐1,1,1,3,3,3‐hexafluoropropan‐2‐ol
• Synonyms: 2‐[2‐bromo‐5‐tert‐butyl‐3‐(1,1,1,3,3,3‐hexafluoro‐2‐hydroxypropan‐2‐yl)phenyl]‐1,1,1,3,3,3‐hexafluoropropan‐2‐ol
• CAS NO: 101697-26-1
• Molecular Weight: 545.163
• Mol File: 101697-26-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2‐[2‐bromo‐5‐tert‐butyl‐3‐(1,1,1,3,3,3‐hexafluoro‐2‐hydroxypropan‐2‐yl)phenyl]‐1,1,1,3,3,3‐hexafluoropropan‐2‐ol(CAS DataBase Reference)
• NIST Chemistry Reference: 2‐[2‐bromo‐5‐tert‐butyl‐3‐(1,1,1,3,3,3‐hexafluoro‐2‐hydroxypropan‐2‐yl)phenyl]‐1,1,1,3,3,3‐hexafluoropropan‐2‐ol(101697-26-1)
• EPA Substance Registry System: 2‐[2‐bromo‐5‐tert‐butyl‐3‐(1,1,1,3,3,3‐hexafluoro‐2‐hydroxypropan‐2‐yl)phenyl]‐1,1,1,3,3,3‐hexafluoropropan‐2‐ol(101697-26-1)

Safety Data

• Hazardous Substances Data: 101697-26-1(Hazardous Substances Data)

Upstream product

• 194734-10-6 2-bromo-5-tert-butylisophthalic acid chloride 
• 98-19-1 5-tert-Butyl-m-xylene 
• 64395-03-5 2-bromo-5-tert-butyl-isophthalic acid 
• 5345-05-1 4-t-butyl-2,6-dimethylbromobenzene 
• 81290-20-2 (trifluoromethyl)trimethylsilane 
• 101697-24-9 1,4-dihydro-8-(1-hydroxy-1-(trifluoromethyl)-2,2,2-trifluoroethyl)-6-tert-butyl-2,2-dimethyl-4,4-bis(trifluoromethyl)-2H-<3,1>benzoxazine 
• 101697-23-8 1,4-dihydro-8-bromo-6-tert-butyl-2,2-dimethyl-4,4-bis(trifluoromethyl)-2H-<3,1>benzoxazine 
• 101697-25-0 4-tert-butyl-2,6-bis<1-hydroxy-1-(trifluoromethyl)-2,2,2-trifluoroethyl>aniline 

Downstream Products

• 101697-31-8 2-[2-Bromo-5-tert-butyl-3-(2,2,2-trifluoro-1-pentafluorophenyloxy-1-trifluoromethyl-ethyl)-phenyl]-1,1,1,3,3,3-hexafluoro-propan-2-ol 

Relevant articles and documents

Electrochemical Generation of Hypervalent Bromine(III) Compounds

In sharp contrast to hypervalent iodine(III) compounds, the isoelectronic bromine(III) counterparts have been little studied to date. This knowledge gap is mainly attributed to the difficult-to-control reactivity of λ3-bromanes as well as to their challenging preparation from the highly toxic and corrosive BrF3 precursor. In this context, we present a straightforward and scalable approach to chelation-stabilized λ3-bromanes by anodic oxidation of parent aryl bromides possessing two coordinating hexafluoro-2-hydroxypropanyl substituents. A series of para-substituted λ3-bromanes with remarkably high redox potentials spanning a range from 1.86 V to 2.60 V vs. Ag/AgNO3 was synthesized by the electrochemical method. We demonstrate that the intrinsic reactivity of the bench-stable bromine(III) species can be unlocked by addition of a Lewis or a Br?nsted acid. The synthetic utility of the λ3-bromane activation is exemplified by oxidative C?C, C?N, and C?O bond forming reactions.