10170-03-3Relevant articles and documents
Isomerization of uroporphyrinogen I octamethyl ester through spiro- pyrrolenine intermediate
Takakura, Hiroyuki,Nomura, Keishi,Tanino, Hideo,Okada, Kunisuke
, p. 2989 - 2992 (1999)
Treatment of uroporphyrinogen I octamethyl ester with 2- mercaptobenzothiazolylmethyl pyrrole derivative in the presence of silver (I) trifrate under anaerobic condition in dichloromethane for 20 h, followed by aerial oxidation of the products, gave a statistical mixture of uroporphyrin I~IV octamethyl esters. It was proposed that this transformation proceeds through a spiro-pyrrolenine as a key intermediate.
Identification of tetrapyrrole compounds excreted by Rhodobacter sphaeroides and sources of the methyl hydrogens of bacteriochlorophyll a biosynthesized by R. sphaeroides, based on13C-NMR spectral analysis of coproporphyrin III tetramethyl ester
Iida, Katsumi,Nakamura, Masayuki,Hanamitsu, Hiroshi,Kajiwara, Masahiro
, p. 1067 - 1069 (2007)
Red-fluorescent tetrapyrrole compounds excreted by Rhodobacter sphaeroides into the culture broth were concluded to be coproporphyrinogen (Copro'gen) III and uroporphyrinogen (Uro'gen) I, based on the 13C-NMR spectral identification of coproporphyrin (Copro) III tetramethyl ester and uroproporphyrin (Uro) I octamethyl ester. The sources of the methyl hydrogens of bacteriochlorophyll a were established by analysis of the 13C-NMR spectra of 2H,13C-Copro III tetramethyl ester chemically derived from 2H,13C-Copro'gen III biosynthesized through the feeding of δ-amino[2-13C]levulinic acid (ALA) to R. sphaeroides in medium containing 50% 2H2O. We confirmed the previous finding that one of the methyl hydrogens was derived from water in the medium during decarboxylation of four acetyl side chains of Uro'gen III to generate Copro'gen III. It was further shown that the other hydrogen atoms, previously reported to be derived from methylene hydrogens at C-2 of ALA, had been exchanged with hydrogen of water in the medium in the biosynthetic pathways leading from ALA to Copro'gen III.
Quantitative analysis of porphyrins in dried blood spots using liquid chromatography-tandem mass spectrometry with pre-column derivatization
Hur, Yeoun,Han, Sang Beom,Kang, Seung Woo,Lee, Youngshin
, p. 3103 - 3106 (2014/12/11)
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