10171-92-3

Basic information

• Product Name: (S)-(+)-2-METHYLGLUTARIC ACID DIMETHYL ESTER
• Synonyms: Dimethyl (S)-(+)-2-Methylglutarate;DIMETHYL (S)-(+)-2-METHYLGLUTARATE;DIMETHYL-(S)-2-METHYLGLUTARATE;(S)-(+)-2-METHYLGLUTARIC ACID DIMETHYL ESTER;(S)-(+)-2-METHYLGLUTARIC ACID DIMETHYL ESTER 95+%
• CAS NO: 10171-92-3
• Molecular Formula: C₈H₁₄O₄
• Molecular Weight: 174.19
• Product Categories: Synthetic Organic Chemistry;Chiral Building Blocks;Esters (Chiral)
• Mol File: 10171-92-3.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 91 °C / 5mmHg
• Flash Point: 90.802 °C
• Appearance: /
• Density: 1,06 g/cm3
• Vapor Pressure: 0.264mmHg at 25°C
• Refractive Index: 24.5 ° (C=neat)
• CAS DataBase Reference: (S)-(+)-2-METHYLGLUTARIC ACID DIMETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-(+)-2-METHYLGLUTARIC ACID DIMETHYL ESTER(10171-92-3)
• EPA Substance Registry System: (S)-(+)-2-METHYLGLUTARIC ACID DIMETHYL ESTER(10171-92-3)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 10171-92-3(Hazardous Substances Data)

Usage

General Description

(S)-(+)-2-Methylglutaric acid dimethyl ester is a chemical compound that belongs to the class of esters. It is a stereochemically pure compound with a specific three-dimensional arrangement of atoms. This chemical is used in various applications such as in the synthesis of pharmaceuticals, fragrances, and other organic compounds. It is also used as a building block in the production of polymers and resins. The compound has a fruity odor and is often used as a flavoring agent in the food industry. Additionally, it is used as a solvent and intermediate in chemical reactions. Overall, (S)-(+)-2-Methylglutaric acid dimethyl ester has a wide range of industrial and commercial applications.

InChI:InChI=1/C8H14O4/c1-6(8(10)12-3)4-5-7(9)11-2/h6H,4-5H2,1-3H3/t6-/m0/s1

Upstream product

• 14035-94-0 dimethyl 2-methylglutarate 
• 471261-18-4 methyl (4S)-(4-methoxy-2-methylphenyl)pentanoate 
• 186581-53-3 diazomethane 
• 75-05-8 acetonitrile 
• 87848-77-9 4-(o-methoxy-p-tolyl)-pentanoic acid methyl ester 
• 1233235-12-5 (S)-5-methoxy-2-methyl-5-oxopentanoic acid 
• 5621-44-3 dimethyl 2-methylenepentanedioate 
• 109943-05-7 (-)-2-Methyl-glutarsaeure-1-methylester-5-<4-methoxycarbonyl-1,5-dimethylhexylester> 
• 74-88-4 methyl iodide 
• 1115-82-8 (S)-2-methylglutaric acid 
• 399535-04-7 methyl 4-(2'-methoxy-5'-methylphenyl)pentanoate 
• 170423-72-0 methyl (4S)-(2-methoxy-4-methylphenyl)pentanoate 
• 29737-67-5 methyl (-)-(E)-2-carbomethoxycyclopropylideneacetate 
• 29979-45-1 methyl (+)-(Z)-2-carbomethoxycyclopropylidene acetate 

Downstream Products

• 1120-62-3 3-methyl-1-cyclopentene 
• 693-89-0 1-methylcyclopent-1-ene 
• 1115-82-8 (S)-2-methylglutaric acid 

Relevant articles and documents

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Esterase catalyzed regio-and enantio-selective hydrolysis of substituted carboxylates

Optically active α-substituted carboxylic acid derivatives were obtained with regio-and enantio-selective hydrolysis catalyzed by esterase from Pseudomonas putida MR-2068. Substrate specificities were summarized in empirical rule to predict the enantiopreferences of the esterase. High regio-selectivities were also discussed with binding models.

Impact on hydrogenation catalytic cycle of the R groups Cyclic feature in "r-SMS-Phos"

A series of R-SMS-Phos ligands was evaluated in the Rh(I)-catalyzed hydrogenation of a set of olefins showing a marked influence of the cyclic nature and structure of the R groups. Overall, cPen- and Cy-SMS-Phos performed efficiently, while Ph- and Bn-SMS-Phos exhibited slower kinetics and furnished lower ees also compared with C6F5CH2-SMS-Phos. The Rh(I)-(Cy-SMS-Phos) catalyst was screened under mild conditions displaying excellent enantioselectivities and high TOFs. Cases of catalysis under catalyst or substrate control were identified.

Sesterterpenoids from the sponge Sarcotragus sp.

Nineteen new sesterterpenoids and eight known compounds were isolated from the sponge Sarcotragus sp. collected from Soheuksan Island, Korea. The structures of these compounds were determined to be linear sesterterpenoids containing furan or related oxygenated functionalities on the basis of combined chemical and spectroscopic analyses. In addition, the configurations of several previously undetermined compounds were assigned. Several compounds exhibited moderate to major antibacterial activity (compounds 1-3, 17, 18) and cytotoxicity (3, 11, 12) against the K562 cell line and inhibitory activity against isocitrate lyase (6, 13).