1115-82-8

Basic information

• Product Name: (S)-(+)-2-METHYLGLUTARIC ACID
• Synonyms: (S)-(-)-2-METHYLGLUTARIC ACID;(S)-(+)-2-METHYLGLUTARIC ACID;(S)-2-METHYLGLUTARIC ACID;(S)-(+)-2-METHYLPENTANEDIOIC ACID;(S)-(-)-2-METHYLGLUTARIC ACID 98+%;(2S)-2-Methylpentanedioic acid;(S)-(+)-2-Methylglutaric Acid
• CAS NO: 1115-82-8
• Molecular Formula: C₆H₁₀O₄
• Molecular Weight: 146.14
• Product Categories: Carboxylic Acids (Chiral);Chiral Building Blocks;Synthetic Organic Chemistry
• Mol File: 1115-82-8.mol
• Article Data: 7

Chemical Properties

• Melting Point: 82°C
• Boiling Point: 332.7 °C at 760 mmHg
• Flash Point: 148.8 °C
• Appearance: /
• Density: 1.246 g/cm³
• Vapor Pressure: 2.76E-05mmHg at 25°C
• Refractive Index: 21 ° (C=5, H2O)
• PKA: 4.57±0.10(Predicted)
• CAS DataBase Reference: (S)-(+)-2-METHYLGLUTARIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-(+)-2-METHYLGLUTARIC ACID(1115-82-8)
• EPA Substance Registry System: (S)-(+)-2-METHYLGLUTARIC ACID(1115-82-8)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 1115-82-8(Hazardous Substances Data)

Usage

Uses

(S)-(+)-2-Methylglutaric Acid is a useful intermediate for organic synthesis. It is used in the preparation of optically active 3-methylcyclopentene.

InChI:InChI=1/C6H10O4/c1-4(6(9)10)2-3-5(7)8/h4H,2-3H2,1H3,(H,7,8)(H,9,10)/t4-/m0/s1

Upstream product

• 13368-64-4 (1S)-3t-methyl-cyclopentane-1r,2c-dicarboxylic acid 
• 109943-05-7 (-)-2-Methyl-glutarsaeure-1-methylester-5-<4-methoxycarbonyl-1,5-dimethylhexylester> 
• 17293-53-7 (S)-1,3-diphenylbutane 
• 346000-86-0 (2S)-2-methyl-5-oxo-5-(2-oxo(1,3-oxazolidin-3-yl))pentanoic acid 
• 18831-15-7 pseudosarsasapogenin 
• 7732-18-5 water 
• 127-09-3 sodium acetate 
• 64-19-7 acetic acid 
• 546-41-8 (22S,25S)-5β,20αH-Spirostan-3β-ol 
• 2634-63-1 di-O-acetyl-cyclopseudomarkogenin 
• 475-27-4 (3aS)-3ξ,6c-dimethyl-(3ar,6ac)-hexahydro-cyclopenta[c]furan-1-one 
• 18069-17-5 2-methylglutaric acid 
• 78339-53-4 (S,Z)-2-methyl-6-(p-tolyl)hept-2-en-1-ol 
• 1121-72-8 (-)-(5S)-5-methyl-tetrahydropyran-2-one 

Downstream Products

• 10171-92-3 (S)-(+)-dimethyl-2-methylglutarate 

Relevant articles and documents

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Stellettazole D, a cytotoxic imidazole alkaloid from the marine sponge Jaspis duoaster

A new cytotoxic imidazole alkaloid, stellettazole D, containing norsesquiterpene and aminopropylimidazolium units, has been isolated from the marine sponge Jaspis duoaster. The structure of stellettazole D was assigned on the basis of NMR, mass spectrometry, and IR spectral data. Stellettazole D has moderate cytotoxicity against a limited number of tumor cells.

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First Direct Synthesis of Optically Active 3-Methylcyclopentene

(-)-(S)- and (+)-(R)-3-methylcyclopentene (1) has been prepared in a stereochemically unambiguous synthesis.The (S)-configuration for (-)-1 was confirmed by correlation with (-)-(S)-1-methylindane.

Asymmetric hydrodimerization of styrene by a chiral zirconium complex containing a tetradentate [OSSO]-type bis(phenolato) ligand

The chiral non racemic (Λ,R,R)-[OSSO]Zr(CH2Ph) 2 (1a) activated by methylaluminoxane (MAO) and in presence of H 2 produces the chiral hydrodimer (S)-1,3-diphenylbutane with good selectivity respect to the achiral 1,4-diphenylbutane. The absolute configuration of the chiral dimer and the effect of the hydrogen pressure on the ratio between 1,3-diphenylbutane and 1,4-diphenylbutane give useful information about the regiochemistry and stereochemistry of insertion of the styrene into the Zr-H bond.