1017238-94-6

Basic information

• Product Name: 13-(4-CHLORO-PHENYL)-3,3-DIMETHYL-2,3,4,13-TETRAHYDRO-INDAZOLO[1,2-B]PHTHALAZINE-1,6,11-TRIONE
• Synonyms: 13-(4-CHLORO-PHENYL)-3,3-DIMETHYL-2,3,4,13-TETRAHYDRO-INDAZOLO[1,2-B]PHTHALAZINE-1,6,11-TRIONE;13-(4-Chlorophenyl)-3,3-dimethyl-2,3,4,13-tetrahydroindazolo[1,2-b]phthalazine-1,6,11-tri
• CAS NO: 1017238-94-6
• Molecular Formula: C₂₃H₁₉ClN₂O₃
• Molecular Weight: 407
• Mol File: 1017238-94-6.mol
• Article Data: 87

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 13-(4-CHLORO-PHENYL)-3,3-DIMETHYL-2,3,4,13-TETRAHYDRO-INDAZOLO[1,2-B]PHTHALAZINE-1,6,11-TRIONE(CAS DataBase Reference)
• NIST Chemistry Reference: 13-(4-CHLORO-PHENYL)-3,3-DIMETHYL-2,3,4,13-TETRAHYDRO-INDAZOLO[1,2-B]PHTHALAZINE-1,6,11-TRIONE(1017238-94-6)
• EPA Substance Registry System: 13-(4-CHLORO-PHENYL)-3,3-DIMETHYL-2,3,4,13-TETRAHYDRO-INDAZOLO[1,2-B]PHTHALAZINE-1,6,11-TRIONE(1017238-94-6)

Safety Data

• Hazardous Substances Data: 1017238-94-6(Hazardous Substances Data)

Usage

Class

Phthalazine triones

Characteristic groups

a. 4-chloro-phenyl group
b. Tetrahydro-indazolo ring system

Potential applications

Pharmaceutical

Biological activities

a. Enzyme inhibition
b. Receptor binding
c. Other pharmacological functions

Research focus

Therapeutic agent for various medical conditions

Further studies

Determine full range of biological effects and potential applications

Upstream product

• 88-96-0 phthalamide 
• 104-88-1 4-chlorobenzaldehyde 
• 126-81-8 dimedone 
• 3645-45-2 phthaloyldihydrazine 
• 88-95-9 Phthaloyl dichloride 
• 136918-14-4 phthalimide 
• 85-44-9 phthalic anhydride 
• 79785-97-0 hydrazine hydrate 
• 7803-57-8 hydrazine hydrate 
• 1445-69-8 2,3-dihydrophthalazine-1,4-dione 
• 3471-13-4 dimedone 
• 28746-59-0 2-[(4-chlorophenyl)methylene]-5,5-dimethylcyclohexane-1,3-dione 

Relevant articles and documents

Novel sultone based Br?nsted acidic ionic liquids with perchlorate counter-anion for one-pot synthesis of 2H?indazolo[2,1?b]phthalazine?triones

Three novel sultone based Br?nsted acidic ionic liquids are introduced. These ionic liquids were prepared in three similar two-steps reactions. The ring opening of 1,4-butane sultone was performed using 1,4-dimethyl piperazine or 1,10-phenantroline as nit

Solvent-free, sonochemical, one-pot, four-component synthesis of 2H-indazolo[2,1-b]phthalazine-triones and 1H-pyrazolo[1,2-b]phthalazine-diones catalyzed by Fe3O4@SiO2-imid-PMAn magnetic nanoparticles

A practical and green method for the synthesis of 2H-indazolo[2,1-b]phthalazine-triones and 1H-pyrazolo[1,2-b]phthalazine-diones using Fe3O4@SiO2-imid-PMAn nanoparticles as an eco-friendly magnetic catalyst from the four-component condensation, solvent-free reaction of phthalic anhydride, hydrazinium hydroxide, 1,3-diketones, and aldehydes under thermal or ultrasound irradiation at room temperature is described. This new procedure has notable advantages such as operational simplicity, excellent yields, short reaction time, and absence of any tedious work-up or purification. In addition, thermal stability, easy preparation and separation of the catalyst make it a good heterogeneous system and a useful alternative to other heterogeneous catalysts. Also, the catalyst can be easily recovered by a magnetic field and reused for eight consecutive reaction cycles without significant loss of activity.

Application of O-sulfonic acid poly(4-vinylpyrrolidonium) chloride as an efficient polymer-supported catalyst in the rapid synthesis of 2H-indazolo[2,1-b]phthalazine-triones and Biginelli-like products

In this work, a series of 2H-indazolo[2,1-b]phthalazine-triones and Biginelli-like products were efficiently synthesized for the first time using O-Sulfonic acid poly(4-vinylpyrrolidonium) chloride ([PVP-SO3H]Cl) as an eco-friendly polymer-supp