1018812-95-7

Basic information

• Product Name: tert-butyl N-(4-acetyl-6-methoxypyridin-3-yl)carbamate
• CAS NO: 1018812-95-7
• Molecular Weight: 266.297
• Mol File: 1018812-95-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: tert-butyl N-(4-acetyl-6-methoxypyridin-3-yl)carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl N-(4-acetyl-6-methoxypyridin-3-yl)carbamate(1018812-95-7)
• EPA Substance Registry System: tert-butyl N-(4-acetyl-6-methoxypyridin-3-yl)carbamate(1018812-95-7)

Safety Data

• Hazardous Substances Data: 1018812-95-7(Hazardous Substances Data)

Upstream product

• 183741-80-2 tert-butyl N-(6-methoxypyridin-3-yl)carbamate 
• 24424-99-5 di-tert-butyl dicarbonate 
• 127-19-5 N,N-dimethyl acetamide 
• 6628-77-9 6-methoxy-pyridin-3-ylamine 
• 78191-00-1 N-Methoxy-N-methylacetamide 

Downstream Products

• 952059-64-2 6-methoxy-1,7-naphthyridin-4(1H)-one 
• 952059-61-9 4-chloro-6-methoxy-1,7-naphthyridine 

Relevant articles and documents

Discovery of a novel series of thienopyrimidine as highly potent and selective PI3K inhibitors

Inhibition of the phosphoinositide 3-kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) signaling pathway provides a promising new approach for cancer therapy. Through a rational design, a novel series of thienopyrimidine was discovered as highly pote

Strategic studies in the syntheses of novel 6,7-substituted quinolones and 7- or 6-substituted 1,6- and 1,7-naphthyridones

This paper describes the different strategies devised and applied to overcome the selectivity issues in the syntheses of 6,7-disubstituted-1H-quinolin-4-one, 7-substituted-1H-1,6-naphthyridin-4-one and 6-substituted-1H-1,7-naphthyridin-4-one derivatives. They allowed us to improve the overall yields and the scaling-up feasibility. Several examples illustrate these strategies with their advantages and drawbacks.