101906-10-9

Basic information

• Product Name: Benzenamine, N-butyl-4-fluoro-
• CAS NO: 101906-10-9
• Molecular Formula: C10H14FN
• Molecular Weight: 167.226
• Mol File: 101906-10-9.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Benzenamine, N-butyl-4-fluoro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenamine, N-butyl-4-fluoro-(101906-10-9)
• EPA Substance Registry System: Benzenamine, N-butyl-4-fluoro-(101906-10-9)

Safety Data

• Hazardous Substances Data: 101906-10-9(Hazardous Substances Data)

Upstream product

• 109-73-9 N-butylamine 
• 460-00-4 1-Bromo-4-fluorobenzene 
• 123-72-8 butyraldehyde 
• 371-40-4 4-fluoroaniline 
• 350-46-9 4-Fluoronitrobenzene 
• 352-33-0 1-Chloro-4-fluorobenzene 
• 106-49-0 p-toluidine 
• 71-36-3 butan-1-ol 
• 109-69-3 n-Butyl chloride 
• 35369-63-2 N-(4-fluorophenyl)butyramide 

Downstream Products

• 55239-55-9 C₁₁H₁₃ClFNO 
• 123-72-8 butyraldehyde 
• 371-40-4 4-fluoroaniline 
• 1621058-26-1 C₂₀H₂₆F₂N₂ 
• 332-07-0 bis-(4-fluorophenyl)diazene 

Relevant articles and documents

Efficient nickel-catalysed: N -alkylation of amines with alcohols

The selective N-alkylation of amines with alcohols via the borrowing hydrogen strategy represents a prominent sustainable catalytic method, which produces water as the only by-product and is ideally suited for the catalytic transformation of widely available alcohol reaction partners that can be derived from renewable resources. Intensive research has been devoted to the development of novel catalysts that are mainly based on expensive noble metals. However, the availability of homogeneous or heterogeneous non-precious metal catalysts for this transformation is very limited. Herein we present a highly active and remarkably easy-to-prepare Ni based catalyst system for the selective N-alkylation of amines with alcohols, that is in situ generated from Ni(COD)2 and KOH under ligand-free conditions. This novel method is very efficient for the functionalization of aniline and derivatives with a wide range of aromatic and aliphatic alcohols as well as diols and exhibits excellent functional group tolerance including halides, benzodioxane and heteroaromatic groups. Several TEM measurements combined with elemental analysis were conducted in order to gain insight into the nature of the active catalyst and factors influencing reactivity.

Selective N-alkylation of arylamines with alkyl chloride in ionic liquids: Scope and applications

An efficient N-selective alkylation of primary aromatic amines in molten quaternary ammonium salts, as the solvent, under relatively mild and base-free conditions is presented. On the basis of the Kamlet-Taft parameters and the nucleophilicity of the IL (ionic liquid) anions, the influence of the ionic liquid was evaluated. This protocol was validated on a larger multigram scale and with the syntheses of bioactive heterocycles (e.g., 1,4-benzothiazine and quinoxalines) and new efficient MALDI matrixes. Copyright

Synthesis and Radiosynthesis for in vivo Imaging Using PET

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