10205-56-8

Usage

Uses

Used in Pharmaceutical Industry:
(4-Benzothiazol-2-yl-phenyl)-dimethyl-amine is used as a building block for the synthesis of various drugs and compounds, playing a crucial role in the development of new medications.
Used in Organic Dyes and Pigments Production:
This chemical compound is utilized in the production of organic dyes and pigments, contributing to the coloration and properties of various products.
Used in Industrial Processes:
(4-Benzothiazol-2-yl-phenyl)-dimethyl-amine is employed in some industrial processes, where its unique chemical properties are leveraged for specific applications.
Used in Research and Development:
(4-Benzothiazol-2-yl-phenyl)-dimethyl-amine has potential applications in research and development, particularly in the fields of medicinal chemistry and material science, where it can be explored for novel uses and properties.
It is important to handle and use (4-Benzothiazol-2-yl-phenyl)-dimethyl-amine with caution due to its potential hazards and reactivity, ensuring safety in its applications across different industries.

InChI:InChI=1/C15H14N2S/c1-17(2)12-9-7-11(8-10-12)15-16-13-5-3-4-6-14(13)18-15/h3-10H,1-2H3

Upstream product

• 50783-26-1 1-(2-methyl-2,3-dihydrobenzothiazol-2-yl)-methyl phenyl ketone 
• 100-10-7 4-dimethylamino-benzaldehyde 
• 38204-92-1 4,4'-bis(dimethylamino)dibenzyl disulfide 
• 137-07-5 2-amino-benzenethiol 
• 619-84-1 p-N,N-dimethylaminobenzoic acid 
• 95-16-9 1,3-Benzothiazole 
• 586-77-6 4-bromo-N,N-dimethylaniline 
• 6278-73-5 2-(4-aminophenyl)benzothiazole 
• 74-88-4 methyl iodide 
• 2516-40-7 2-bromo-1,3-benzothiazole 
• 28611-39-4 4-(dimethylamino)benzene-boronic acid 
• 31646-31-8 4-[(4-dimethylamino-phenyl)-methylsulfanyl-methylene]-morpholinium; iodide 
• 1009609-63-5 C₃₀H₃₀N₄S₂ 
• 1326245-58-2 3-(2-aminophenylsulfanyl)-3-(4-N,N-dimethylaminophenyl)-2-nitro-1-phenylpropan-1-one 

Downstream Products

• 20144-01-8 2-(4-dimethylamino-phenyl)-3-ethyl-benzothiazolium; iodide 
• 4870-76-2 2-{4-(dimethylamino)phenyl}-3-methylbenzothiazolium iodide 
• 55489-33-3 2-[2’-methyl,4’-(dimethylamino)phenyl]benzothiazole 

Relevant academic research and scientific papers

Visible-light-driven synthesis of 2-substituted benzothiazoles using CdS nanosphere as heterogenous recyclable catalyst

This Letter reports simple, green, and efficient synthesis of mesoporous CdS nanosphere (CdSNS) and its application as heterogeneous catalyst for the synthesis of 2-substituted benzothiazole. We report, for the first time, the synthesis of 2-substituted benzothiazoles from various aryl and alkyl aldehydes under visible light irradiation at room temperature. CdSNS catalyst generated in water demonstrates excellent catalytic activity for both the alkyl and aryl aldehydes, with good recyclability. The reaction yield is high for the electron-donating and electron withdrawing substituents as well as heterocyclic aldehydes with good turn over number (TON) and turnover frequency (TOF).

Identifying the bond responsible for the fluorescence modulation in an amyloid fibril sensor

An ultrafast intramolecular bond twisting process is known to be the responsible mechanism for the sensing activity of the extensively used amyloid fibril sensor thioflavin T (ThT). However, it is not yet known which one of the two possible single bonds in ThT is actually involved in the twisting process. To resolve this fundamental issue, two derivatives of ThT have been designed and synthesized and subsequently their photophysical properties have been studied in different solvents. It is understood from the present study that the rotation around the central C-C single bond, and not that around the C-N single bond, is primarily responsible for the sensor activity of ThT. Detailed viscosity-dependent fluorescence studies revealed that the ThT derivative with restricted C-N bond rotation acts as a better sensor than the derivative with free C-N bond rotation. The better sensory activity is directly correlated with a shorter excited-state lifetime. Results obtained from the photophysical studies of the ThT derivatives have also been supported by the results obtained from quantum chemical calculations.

Metal-organic framework mediated expeditious synthesis of benzimidazole and benzothiazole derivatives through an oxidative cyclization pathway

Herein, we report the facile synthesis of various benzimidazoles and benzothiazoles by using the NH2-MIL-125(Ti) MOF as an efficient oxidant-free heterogeneous catalyst with good yield. Adsorption of the substrate on the NH2-MIL-125(Ti) MOF surface through electron deficient Ti4+ sites initiates the reaction. The broad substrate scope and high reusability of this catalyst are attractive for synthesis of a wide range of medicinally active benzimidazole and benzothiazole derivatives.

Bienzymatic synthesis of benzothia/(oxa)zoles in aqueous medium

A series of 2-arylbenzothiazoles and 2-arylbenzoxazoles were synthesized by the reactions of aldehydes and 2-aminothiophenol and 2-hydroxythiophenol, respectively, using glucose oxidase (GOX)-chloroperoxidase (CPO) catalytic system under oxygen atmosphere.

Bismuth nitrate as an efficient catalyst for the preparation of 2-arylbenzothiazole derivatives

A simple and eco-friendly procedure for synthesis of 2-arylbenzothiazoles in high yields by cyclo-condensation reaction of 2-aminothiophenol and aldehydes in the presence of bismuth nitrate (Bi(NO3)3) as heterogeneous catalyst is des

Sodium dithionite-promoted synthesis of 2-arylbenzothiazoles by reaction of 2,2′-disulfanediyldianiline with aldehydes in water

Sodium dithionite-promoted synthesis of 2-arylbenzothiazoles by reaction of 2,2′-disulfanediyldianiline with aldehydes in the presence of sodium dodecyl sulfate in water has been developed. Possible reaction pathways are discussed and the effects of different promoter on the reaction are investigated. The important features of this methodology are simple work-up, environmentally benign, high yields, metal-free, and inexpensive reagents.

Sulfamic acid as a recyclable and green catalyst for rapid and highly efficient synthesis of 2-arylbenzothiazoles in water at room temperature

2-Arylbenzothiazoles have been synthesized in water in good to excellent yield from direct condensation of various aromatic aldehydes with 2-aminothiophenol promoted by catalytic amount of sulfamic acid at room temperature. This method provides a simple,

Camphor sulfonic acid catalyzed a simple, facile, and general method for the synthesis of 2-arylbenzothiazoles, 2-arylbenzimidazoles, and 3H-spiro[benzo[d]thiazole-2,3′-indolin]-2′-ones at room temperature

A simple, mild, eco-friendly, general, and convenient approach has been developed for the synthesis of structurally diverse 2-arylbenzothiazole derivatives from the reactions of 2-aminothiophenol and various aromatic aldehydes using camphor sulfonic acid

Epichlorohydrin cross-linked β -cyclodextrin: An environmental method for the synthesis of 2-arylbenzothiazoles derivatives in water

In the present study, we report an environmentally benign synthesis of 2-arylbenzothiazoles derivatives from o-aminothiophenol and aldehydes in aqueous medium using β-cyclodextrin polymer as a catalyst and air as an oxidant. The polymer showed excellent c

A simple and eco-friendly process catalyzed by montmorillonite K-10, with air as oxidant, for synthesis of 2-substituted benzothiazoles

Simple and eco-friendly synthesis of 2-substituted benzothiazoles is described. The reaction is performed in absolute ethanol at room temperature, using a catalytic amount of montmorillonite K-10, and with continuous bubbling of air as oxidant. Simplicity