102093-90-3

Upstream product

• 18162-48-6 tert-butyldimethylsilyl chloride 
• 102208-53-7 (3R,4R,5R)-5-hydroxy-3,4,6-tribenzyloxy-1-hexene 
• 69739-34-0 t-butyldimethylsiyl triflate 
• 160549-10-0 2,3,5-tri-O-benzyl-D-arabinofuranose 

Downstream Products

• 1337989-86-2 tert-butyldimethyl((2R,3S,4R)-1,3,4-tris(benzyloxy)-4-(oxiran-2-yl)butan-2-yloxy)silane 
• 1337989-87-3 5-((tetrahydro-2H-pyran-2-yloxy)methyl)-1-((3R,4S,5R)-3,4,6-tris(benzyloxy)-5-(tert-butyldimethylsilyloxy)-2-hydroxyhexyl)-1H-pyrrole-2-carbaldehyde 
• 1337989-88-4 5-((tetrahydro-2H-pyran-2-yloxy)methyl)-1-((3S,4S,5R)-3,4,6-tris(benzyloxy)-5-(tert-butyldimethylsilyloxy)-2-oxohexyl)-1H-pyrrole-2-carbaldehyde 
• 1337989-89-5 (2S,3S,4R,5R)-3,4-bis(benzyloxy)-5-(benzyloxymethyl)-1',4,4',5-tetrahydro-3H-spiro[furan-2,3'-pyrrolo[2,1-c][1,4]oxazine]-6'-carbaldehyde 
• 1337990-07-4 (2R,3S,4R,5R)-3,4-bis(benzyloxy)-5-(benzyloxymethyl)-1',4,4',5-tetrahydro-3H-spiro[furan-2,3'-pyrrolo[2,1-c][1,4]oxazine]-6'-carbaldehyde 
• 115149-91-2 [(E)-(3R,4S,5R)-3,4,6-Tris-benzyloxy-5-(tert-butyl-dimethyl-silanyloxy)-hex-1-enyl]-phosphonic acid diphenyl ester 
• 115149-92-3 [(E)-(3R,4S,5R)-3,4,6-Tris-benzyloxy-5-(tert-butyl-dimethyl-silanyloxy)-hex-1-enyl]-phosphonic acid diethyl ester 
• 102292-67-1 2,5-anhydro-3,4,6-tri-O-benzyl-1-deoxy-1-diethoxyphophinoyl-D-mannitol 
• 102341-44-6 2,5-anhydro-3,4,6-tri-O-benzyl-1-deoxy-1-diethoxyphophinoyl-D-glucitol 
• 78009-77-5 2,3,5-tri-O-benzyl-4-O-(tert-butyldimethylsilyl)-aldehydo-D-arabinose 

Relevant academic research and scientific papers

Total synthesis and stereochemical revision of acortatarins A and B

A first total synthesis of acortatarins A, B, and an enantiomer of the proposed structure of acortatarin B is described by using readily available d-sugars. This convergent total synthesis revealed the revision of the absolute configuration of acortatarin A and structural revision of acortatarin B. The key steps involved are regioselective epoxide opening with deprotonated 2,5-disubstituted pyrrole and spiroketalization.

SYNTHESIS OF C-ARABINOFURANOSYL COMPOUNDS. PHOSPHONATE AND CARBOXYLATE ISOESTERS OF D-ARABINOSE 1,5-BISPHOSPHATE

Electrophile-mediated cyclization of 3,4,6-tri-O-benzyl-1,2-dideoxy-D-arabino-hex-1-enitol with N-bromosuccinimide yielded primarily 2,5-anhydro-3,4,6-tri-O-benzyl-1-bromo-1-deoxy-D-glucitol (10).This apparently kinetically controlled reaction was of key