102096-63-9Relevant academic research and scientific papers
Enantioselective total synthesis of sesquiterpenoid phellilane L and its diastereomer
Kumaraswamy, Gullapalli,Ramesh, Vankudoth,Vijaykumar, Swargam
, (2021)
The enantioselective synthesis of phellilane L has been accomplished in six-steps with overall 36% yield. The quinidine-based organocatalytic cyclopropanation of vinyl-ketone with 2-bromo-N,O-dimethylacetamide for the stereoselective construction of subst
Silent catalytic promiscuity in the high-fidelity terpene cyclase δ-cadinene synthase
Loizzi, Marianna,Miller, David J.,Allemann, Rudolf K.
, p. 1206 - 1214 (2019/02/07)
δ-Cadinene synthase (DCS) is a high-fidelity sesquiterpene synthase that generates δ-cadinene as the sole detectable organic product from its natural substrate (E,E)-FDP. Previous work with this enzyme using substrate analogues revealed the ability of DCS
THIOPHEN-2-CARBOXYLIC ACID DERIVATIVES USEFUL AS INHIBITORS OF FLAVIVIRIDAE VIRUSES
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Page/Page column 35, (2013/03/26)
Provided are compounds of Formula I: and pharmaceutically acceptable salts and esters thereof. The compounds, compositions, and methods provided are useful for the treatment of Flaviviridae virus infections (e.g. hepatitis C infections), particularly drug
INHIBITORS OF FLAVIVIRIDAE VIRUSES
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Page/Page column 106, (2011/02/18)
Provided are compounds of Formula I: and pharmaceutically acceptable salts and esters thereof. The compounds, compositions, and methods provided are useful for the treatment of Flaviviridae virus infections, particularly hepatitis C infections.
INHIBITORS OF FLAVIVIRIDAE VIRUSES
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Page/Page column 97, (2011/04/18)
Provided are compounds of Formula I: and pharmaceutically acceptable salts and esters thereof. The compounds, compositions, and methods provided are useful for the treatment of Flaviviridae virus infections, particularly hepatitis C infections.
Asymmetric synthesis of highly enantiomerically enriched (S)(-)-β-bisabolene
Argenti,Bellina,Carpita,Rossi
, p. 2909 - 2921 (2007/10/03)
(S)-β-Bisabolene, (S)-1, was synthesized by a synthetic route in which (S)-4-methyl-3-cyclohexene carboxylic acid, (S)-10, which was the key intermediate, was prepared via a highly diastereoselective TiCl4-catalyzed Diels-Alder reaction between
DIASTEREOFACE-DISCRIMINATIVE METAL COORDINATION IN ASYMMETRIC SYNTHESIS: D-PANTOLACETONE AS PRACTICAL CHIRAL AUXILIARY FOR LEWIS ACID CATALYZED DIELS-ALDER REACTIONS
Poll, Thomas,Sobczak, Andrzej,Hartmann, Horst,Helmchen, Gunter
, p. 3095 - 3098 (2007/10/02)
TiCl4-catalyzed Diels-Alder additions of the acrylate of commercial D-pantoloacetone to cyclopentadiene, isoprene and butadiene proceed with very high diastereofacial selectivity.Practical and mechanistic aspects of these reactions are discussed.
