102276-52-8Relevant academic research and scientific papers
Trapping of carbamic acid species with (trimethylsilyl)diazomethane
Ito, Yoshikatsu,Ushitora, Hiromi
, p. 226 - 235 (2006)
Methoxycarbonylation of a variety of amines into the corresponding methyl carbamates was accomplished by allowing them to react with (trimethylsilyl) diazomethane TMSCHN2 under bubbling of CO2. The reaction was performed at room temperature for a period of ca. 2 h in benzene-MeOH (4/1 v/v), which was the solvent of choice. In this mixed solvent, undesirable bicarbonate is formed in equilibrium along with carbamate anion. Owing to the irreversibility in the esterification step by TMSCHN2, however, the yield of methyl carbamate can reach very high.
The Reactivity of Difluorocarbene with Hydroxylamines: Synthesis of Carbamoyl Fluorides
Baars, Hannah,Engel, Julien,Mertens, Lucas,Meister, Daniela,Bolm, Carsten
supporting information, p. 2293 - 2299 (2016/07/29)
Carbamoyl fluorides are formed in reactions of hydroxylamines with difluorocarbene generated from sodium bromodifluoroacetate as readily available and non-toxic carbene precursor. The process shows a high functional group tolerance, and the reaction path has been rationalized by computational calculations. (Figure presented.) .
CATALYST COMPOUNDS
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Paragraph 0314; 0327, (2015/03/28)
The present invention relates to an iridium-based catalyst compound for hydrogenating reducible moieties, especially imines and iminiums, the catalyst compounds being defined by the formulas: where ring B is either itself polycyclic, or ring B together with R is polycyclic. The catalysts of the invention are particularly effective in reductive amination procedures 10 which involve the in situ generation of the imine or iminium under reductive hydrogenative conditions.
A CONVENIENT METHOD FOR THE CONVERSION OF AMINES TO CARBAMATES
Raucher, Stanley,Jones, David S.
, p. 1025 - 1032 (2007/10/02)
Treatment of primary or secondary amines with bis(trimethylsilyl)acetamide followed by addition of methyl, vinyl, or 2,2,2-trichloroethyl chloroformate provides a convenient method for the preparation of the corresponding carbamates.
