10228-54-3Relevant academic research and scientific papers
VANCOMYCIN DERIVATIVE, AND PREPARATION METHOD AND APPLICATION THEREOF
-
Paragraph 0220; 0222-0223, (2016/08/17)
The present invention provides a vancomycin derivative, and a preparation method and an application thereof. The vancomycin derivative of the present invention is obtained by introducing a glycerate moiety between a vancomycin derivative and a liposoluble
Design and synthesis of new vancomycin derivatives
Gu, Wen,Chen, Bei,Ge, Min
, p. 2305 - 2308 (2014/05/20)
A set of vancomycin derivatives with lipid chain attached via a glyceric acid linker was designed and synthesized. A concise synthesis towards these derivatives was developed and the IC50s of these new lipoglycopeptides were tested. Some of them showed very potent activity against both vancomycin sensitive and resistant strains.
Reaction of methyl diazoacetate with aldehydes, amines, thiols, alcohols and acids over transition metal-exchanged clays
Phukan, Prodeep,Mohan, Jakkam Madan,Sudalai, Arumugam
, p. 3685 - 3689 (2007/10/03)
Metal-exchanged clays (M = Rh and Cu) catalyze effectively the reaction of methyl diazoacetate with various aldehydes, affording the corresponding β-keto esters in high yields. They have also been effective in the decomposition of methyl diazoacetate to form metallocarbenes which, in turn, successfully insert into X-H (X = N, O, S, CO2) bonds of a variety of amines, aldehydes, thiols and acids, thereby producing the corresponding esters. The Royal Society of Chemistry 1999.
