10242-05-4

Basic information

• Product Name: 2-[(3-chlorophenyl)amino]acetic acid
• Synonyms: 2-[(3-chlorophenyl)amino]acetic acid;(3-CHLOROANILINO)ACETIC ACID;OTAVA-BB 1142608;2-[(3-chlorophenyl)amino]ethanoic acid;N-(3-chlorophenyl)glycine
• CAS NO: 10242-05-4
• Molecular Formula: C₈H₈ClNO₂
• Molecular Weight: 185.609
• Mol File: 10242-05-4.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• CAS DataBase Reference: 2-[(3-chlorophenyl)amino]acetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[(3-chlorophenyl)amino]acetic acid(10242-05-4)
• EPA Substance Registry System: 2-[(3-chlorophenyl)amino]acetic acid(10242-05-4)

Safety Data

• Hazardous Substances Data: 10242-05-4(Hazardous Substances Data)

Usage

Type of compound

Amino acid derivative

Key functional group

Chlorophenyl group

Potential therapeutic applications

Treatment of cancer, neurological disorders, anti-inflammatory and analgesic agent

Inhibits growth of

Certain cancer cells

Under investigation for

Role in neurotransmission and effects on the central nervous system

Additional research needed

To fully understand its pharmacological properties and potential applications.

Upstream product

• 105-36-2 ethyl bromoacetate 
• 108-42-9 3-chloro-aniline 
• 2573-31-1 ethyl 2-((3-chlorophenyl)amino)acetate 
• 79-11-8 chloroacetic acid 

Downstream Products

• 52827-03-9 N-(3-chloro-phenyl)-N-nitroso-glycine 
• 132465-70-4 N-[(4-chloro-phenoxy)-acetyl]-N-(3-chloro-phenyl)-glycine 

Relevant articles and documents

Perovskite as Recyclable Photocatalyst for Annulation Reaction of N-Sulfonyl Ketimines

A sustainable and cost-effective manner for the photocatalytic annulation reaction of N-sulfonyl ketimines with N-arylglycines to synthesize imidazolidine-fused sulfamidates (31 examples) by employing CsPbBr3 as a heterogeneous photocatalyst has been developed. The catalyst CsPbBr3 can be simply recovered from the reaction mixture and reused at least five times without an obvious reduction in its photocatalytic reactivity, exhibiting a high catalyst economic feature.

INHIBITORS OF BRUTON'S TYROSINE KINASE

This application discloses compounds according to generic Formula I: wherein all variables are defined as described herein, which inhibit Btk. The compounds disclosed herein are useful to modulate the activity of Btk and treat diseases associated with exc

Synthesis and evaluation of phenyl substituted sydnones as potential DPPH-radical scavengers

A series of phenyl substituted sydnones has been synthesized and their radical-scavenging activity has been studied on DPPH free radical. Out of eighteen compounds screened, nine compounds show interesting activity. A mechanism is presented whereby sydnones scavenge DPPH radical through donating H-atom at 4th-position. Its strong radical-scavenging activity mainly arises from 1, 2, 3-oxadiazolium-5-olate ring. Different substituents and their positions on the phenyl ring differently influence DPPH scavenging activity and therefore, may provide clues to design and develop better free-radical scavenging sydnones with multiple activities.