2573-31-1

Basic information

• Product Name: N-(3-Chlorophenyl)-glycine ethyl ester
• Synonyms: ethyl 2-[(3-chlorophenyl)amino]ethanoate;ethyl N-(3-chlorophenyl)glycinate;NSC190338;Oprea1_287858;ST5011894;ZINC00287781;N-(3-Chlorophenyl)-glycine ethyl ester;(3-Chloro-phenylamino)-acetic acid ethyl ester
• CAS NO: 2573-31-1
• Molecular Formula: C₁₀H₁₂ClNO₂
• Molecular Weight: 213.67
• Mol File: 2573-31-1.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 314.5°Cat760mmHg
• Flash Point: 144°C
• Appearance: /
• Density: 1.229g/cm³
• Vapor Pressure: 0.000465mmHg at 25°C
• Refractive Index: 1.562
• CAS DataBase Reference: N-(3-Chlorophenyl)-glycine ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3-Chlorophenyl)-glycine ethyl ester(2573-31-1)
• EPA Substance Registry System: N-(3-Chlorophenyl)-glycine ethyl ester(2573-31-1)

Safety Data

• Hazardous Substances Data: 2573-31-1(Hazardous Substances Data)

Usage

General Description

N-(3-Chlorophenyl)-glycine ethyl ester is a chemical compound that is also known by its IUPAC name, ethyl 2-amino-3-chlorobenzoate. It is an ester derivative of the amino acid glycine, with an ethyl group attached to the carboxyl group. N-(3-Chlorophenyl)-glycine ethyl ester is primarily used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It has also been studied for its potential biological activity and pharmacological properties, particularly as a potential anticonvulsant and analgesic agent. Additionally, it is used as a building block in the synthesis of various organic compounds, making it a versatile and important chemical in the field of organic chemistry.

InChI:InChI=1/C10H12ClNO2/c1-2-14-10(13)7-12-9-5-3-4-8(11)6-9/h3-6,12H,2,7H2,1H3

Upstream product

• 105-39-5 chloroacetic acid ethyl ester 
• 108-42-9 3-chloro-aniline 
• 105-36-2 ethyl bromoacetate 
• 623-73-4 diazoacetic acid ethyl ester 

Downstream Products

• 14108-41-9 2-(3-chlorophenyl-1-ylamino)acethydroxamic acid 
• 10242-05-4 2-((3-chlorophenyl)amino)acetic acid 
• 1493802-25-7 ethyl 2-(N-(3-chlorophenyl)-2-(N-phenylacetamido)acetamido)-acetate 
• 2371-30-4 2-((3-chlorophenyl)amino)acetohydrazide 
• 86323-78-6 [(3-Chloro-phenyl)-(3-mercapto-2-methyl-propionyl)-amino]-acetic acid 

Relevant articles and documents

Perovskite as Recyclable Photocatalyst for Annulation Reaction of N-Sulfonyl Ketimines

A sustainable and cost-effective manner for the photocatalytic annulation reaction of N-sulfonyl ketimines with N-arylglycines to synthesize imidazolidine-fused sulfamidates (31 examples) by employing CsPbBr3 as a heterogeneous photocatalyst has been developed. The catalyst CsPbBr3 can be simply recovered from the reaction mixture and reused at least five times without an obvious reduction in its photocatalytic reactivity, exhibiting a high catalyst economic feature.

Ethyl cellulose derived porous iron@N-doped carbon material for N–H carbene insertion reaction

A newly developed, facile and sustainable strategy, in which zinc salt, melamine and ethyl cellulose are applied as pore-forming agent, nitrogen and carbon source respectively, has been disclosed for the synthesis of Fe/N-codoped carbon materials. This material exhibits excellent catalytic efficiency towards N–H carbene insertion reaction for the synthesis of unnatural amino acid derivatives. Fe/FeOx nanoparticles tranfer electrons to N-doped carbon owing to the Mott-Schottky Effect, which is beneficial to the formation of iron carbene intermediate. N-doping can offer more Lewis base sites, which promotes the proton transfer process. Fe/FeOx nanoparticles are coated with graphitic carbon, thereby avoiding the loss and deactivation of iron sites in this material. Therefore, this material can be reused at least four times without significant loss in activity.

FERROCHELATASE INHIBITORS AND METHODS OF USE

The invention relates to a method of treatment of a patient with a ferrochelatase inhibitor, or a pharmaceutically acceptable salt thereof, or a derivative thereof. Also, the invention relates to a method of treatment of a patient with a ferrochelatase in