10249-21-5Relevant academic research and scientific papers
Synthesis of highly potent novel anti-tubercular isoniazid analogues with preliminary pharmacokinetic evaluation
Ramani, Addepalli Venkata,Monika, Arumalla,Indira, Vadlamani Lakshmi,Karyavardhi, Gopisetti,Venkatesh, Jangala,Jeankumar, Variam Ullas,Manjashetty, Thimmappa H.,Yogeeswari, Perumal,Sriram, Dharmarajan
, p. 2764 - 2767 (2012)
Thirty two novel isoniazid analogues were prepared by one-pot three component condensations of isoniazid (INH), 3-mercaptopropionic acid and various aryl/heteroaryl aldehydes. The synthesized compounds were evaluated for their anti-TB activity against Myc
