1027476-73-8Relevant academic research and scientific papers
Synthesis of isoindolobenzazepine alkaloids based on radical reactions or Pd(0)-catalyzed reactions
Onozaki, Yu,Kurono, Nobuhito,Senboku, Hisanori,Tokuda, Masao,Orito, Kazuhiko
experimental part, p. 5486 - 5495 (2009/12/06)
(Chemical Equation Presented) Methods for synthesis of a ring system characteristic of isoindolobenzazepine alkaloids were studied. Synthesis of lennoxamine and a formal synthesis of chelenine were accomplished in a short route via radical or Pd(0)-cataly
New cyclization route to the skeletons of lennoxamine and chilenine
Kim, Guncheol,Lee, Ki Youn,Yoo, Chul-Hwan
, p. 3251 - 3259 (2008/12/23)
A new cyclization route, triggered by epoxide opening, has been performed to provide the key intermediates for isoindolobenzapine alkaloids, lennoxamine and chilenine. The epoxide was prepared by the Stille reaction using vinyltributylstannane and the fol
An efficient method for the synthesis of enol ethers and enecarbamates. Total syntheses of isoindolobenzazepine alkaloids, lennoxamine and chilenine
Fuwa, Haruhiko,Sasaki, Makoto
, p. 1849 - 1853 (2008/02/10)
An efficient method for the synthesis of enol ethers and enecarbamates has been developed based on catalytic hydrosilane reduction of α-phosphonoxy enol ethers and α-phosphonoxy enecarbamates. This method has been applied to the total syntheses of two iso
Total synthesis of (±)-lennoxamine and (±)-aphanorphine by intramolecular electrophilic aromatic substitution reactions of 2-amidoacroleins
Fuchs, James R.,Funk, Raymond L.
, p. 3923 - 3925 (2007/10/03)
equation presented Intramolecular electrophilic aromatic substitution reactions of 2-amidoacroleins constitute the key steps in the total syntheses of lennoxamine and aphanorphine. The aldehyde moiety of one cyclization product was transformed to a double
