60555-93-3Relevant articles and documents
A short synthesis of lennoxamine via ynamides
Couty, Sylvain,Meyer, Christophe,Cossy, Janine
, p. 767 - 769 (2006)
Lennoxamine was synthesized in eight steps from 2,3-dimethoxybenzoic acid via an intermediate ynamide by using palladium-catalyzed Heck-Suzuki-Miyaura domino reactions.
Microwave-assisted domino hydroformylation/cyclization reactions: Scope and limitations
Airiau, Etienne,Chemin, Claire,Girard, Nicolas,Lonzi, Giacomo,Mann, Andre,Petricci, Elena,Salvadori, Jessica,Taddei, Maurizio
experimental part, p. 2901 - 2914 (2010/10/21)
Hydroformylation of alkenes can be carried out in short time and with low syngas pressure under microwave (MW) dielectric heating. Alkenes, carrying O-, N-, or C-nucleophilic fragments, can be designed for domino reactions, mainly cyclocondensations. Ally
Structure-activity relationship studies of phenanthridine-based Bcl-X L inhibitors
Bernardo, Paul H.,Wan, Kah-Fei,Sivaraman, Thirunavukkarasu,Xu, Jin,Moore, Felicity K.,Hung, Alvin W.,Mok, Henry Y. K.,Yu, Victor C.,Chai, Christina L. L.
experimental part, p. 6699 - 6710 (2009/10/23)
Despite their structural similarities, the natural products chelerythrine (5) and sanguinarine (6) target different binding sites on the pro-survival Bcl-XL protein. This paper details the synthesis of phenanthridine-based analogues of the natu