102783-28-8 Usage
Uses
Used in Biochemical Research:
2-Deoxy-alpha-D-ribose 1-phosphate di(monocyclohexyl-ammonium) salt is used as a research tool for studying the structure and function of DNA and RNA. Its unique properties allow scientists to investigate the interactions between nucleic acids and other biomolecules, contributing to a deeper understanding of genetic processes.
Used in Pharmaceutical Development:
2-DEOXY-ALPHA-D-RIBOSE 1-PHOSPHATE DI(MONOCYCLOHEXYL-AMMONIUM) SALT is utilized in the development of pharmaceuticals targeting genetic and metabolic disorders. Its potential therapeutic applications stem from its ability to interact with DNA and RNA, offering a means to modulate gene expression and metabolic pathways, thereby addressing the underlying causes of certain diseases.
Used in Genetic Disorders Treatment:
2-Deoxy-alpha-D-ribose 1-phosphate di(monocyclohexyl-ammonium) salt is used as a therapeutic agent for the treatment of genetic disorders. Its interaction with nucleic acids may enable the correction or modulation of mutated genes, offering a potential avenue for treating hereditary conditions.
Used in Metabolic Disorders Treatment:
In the treatment of metabolic disorders, 2-DEOXY-ALPHA-D-RIBOSE 1-PHOSPHATE DI(MONOCYCLOHEXYL-AMMONIUM) SALT serves as a potential therapeutic agent. Its ability to influence DNA and RNA interactions may help regulate metabolic pathways, providing a means to address the imbalances associated with various metabolic diseases.
Used in the Development of Drug Delivery Systems:
2-Deoxy-alpha-D-ribose 1-phosphate di(monocyclohexyl-ammonium) salt may also be employed in the development of drug delivery systems, particularly for targeted therapies. Its unique properties could enhance the delivery of therapeutic agents to specific cells or tissues, improving the efficacy and reducing the side effects of treatments.
Check Digit Verification of cas no
The CAS Registry Mumber 102783-28-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,2,7,8 and 3 respectively; the second part has 2 digits, 2 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 102783-28:
(8*1)+(7*0)+(6*2)+(5*7)+(4*8)+(3*3)+(2*2)+(1*8)=108
108 % 10 = 8
So 102783-28-8 is a valid CAS Registry Number.
102783-28-8Relevant academic research and scientific papers
Komatsu, Hironori,Awano, Hirokazu
, p. 5419 - 5421 (2002)
A first stereoselective synthesis of bis(cyclohexylamine) 2-deoxy-alpha-D-ribosyl-1-phosphate has been achieved. The synthesis features a key crystallization-induced asymmetric transformation (AT) to generate a desired alpha-anomer in 99% yield at a 98.8:1.2 ratio of alpha/beta.
Enzymatic Synthesis of 2-Deoxyribose 1-Phosphate and Ribose 1 Phosphate and Subsequent Preparation of Nucleosides
Kulikova, Irina V.,Drenichev, Mikhail S.,Solyev, Pavel N.,Alexeev, Cyril S.,Mikhailov, Sergey N.
, p. 6999 - 7004 (2019/11/13)
α-Ribose-1-phosphate (Rib-p) and 2-deoxy-α-ribose-1-phosphate (dRib-p) are key intermediates in nucleoside metabolism and are important starting compounds for the enzymatic synthesis of various modified nucleosides. To date, chemical and enzymatic methods allowed the preparation of these compounds in rather low yields (11–37 %). This prevents their widespread use for the enzymatic synthesis of biologically active and practically important nucleosides. Here we propose to use 7-methyl-2′-deoxyguanosine (7-Me-dGuo) and 7-methylguanosine (7-Me-Guo) for the preparation of dRib-p and Rib-p. In this paper, we present the effective preparation of Rib-p and dRib-p starting from readily prepared 7-methylguanosine derivatives via their irreversible enzymatic phosphorolysis in the presence of purine nucleoside phosphorylase. Rib-p and dRib-P are obtained in nearly quantitative yields (HPLC analysis) and 74–96 % yields after their isolation and purification, which is much higher than previously reported.
