10286-88-1

Basic information

• Product Name: N-(2,6-Dichlorophenyl)benzamide
• Synonyms: N-(2,6-Dichlorophenyl)benzamide
• CAS NO: 10286-88-1
• Molecular Formula: C₁₃H₉Cl₂NO
• Molecular Weight: 266.12
• Mol File: 10286-88-1.mol
• Article Data: 6

Chemical Properties

• Melting Point: 158-159 °C
• Boiling Point: 296.5±30.0 °C(Predicted)
• Appearance: /
• Density: 1.384±0.06 g/cm3(Predicted)
• PKA: 11.65±0.70(Predicted)
• CAS DataBase Reference: N-(2,6-Dichlorophenyl)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2,6-Dichlorophenyl)benzamide(10286-88-1)
• EPA Substance Registry System: N-(2,6-Dichlorophenyl)benzamide(10286-88-1)

Safety Data

• Hazardous Substances Data: 10286-88-1(Hazardous Substances Data)

Upstream product

• 82344-31-8 N-(o-chlorophenyl)benzohydroxamic acid 
• 157491-02-6 (E)-2,6-dichlorobenzophenone oxime 
• 93-89-0 benzoic acid ethyl ester 
• 76-83-5 trityl chloride 
• 2904-62-3 2,6-dichlorobenzonitrile N-oxide 
• 90-99-3 diphenylchloromethane 
• 13391-37-2 1-(chlorophenylmethyl)-3-methoxybenzene 
• 341-02-6 trityl tetrafluoroborate 
• 10468-16-3 2-chloro-N-hydroxybenzenamine 
• 98-88-4 benzoyl chloride 
• 608-31-1 2,6-Dichloroaniline 
• 93-58-3 benzoic acid methyl ester 

Downstream Products

• 137090-09-6 N-(2,6-Dichloro-phenyl)-N-methyl-benzamide 
• 608-31-1 2,6-Dichloroaniline 

Relevant articles and documents

Microwave-Assisted Organic Synthesis, structure–activity relationship, kinetics and molecular docking studies of non-cytotoxic benzamide derivatives as selective butyrylcholinesterase inhibitors

A series of benzamide derivatives 1–12 with various functional groups (–H, –Br, –F, –OCH3, –OC2H5, and –NO2) was synthesized using an economic, and facile Microwave-Assisted Organic Synthesis, and evaluated for

Reactions between nitrile oxides and carbenium ions: Synthesis of benzoxazines, oximes, and amides through intramolecular ortho or ipso attack

Reactions between nitrile oxides and benzylic carbocations are described. Different results were obtained when the carbocations were generated from the corresponding chlorides with different Lewis acids, with addition products such as benzoxazines, oximes, and amides being produced. Primary, secondary, and tertiary carbocations showed different reactivities. The product ratios strongly depended on the substituents on the aromatic ring of the benzylic carbocations. Evidence for the proposed mechanism is reported. Wiley-VCH Verlag GmbH, 69451 Weinheim, Germany, 2002.

Novel Reactions: Part I - Facile Synthesis of Substituted ortho-Chloranilines from Nitrobenzene Derivatives

N-Substituted benzo and acetohydroxamic acids (5), prepared from N-arylhydroxylamines and benzoyl or acetyl chloride, react readily with thionyl chloride at low temperature to give ortho-chloroanilide derivatives (6) in good yield.The latter (6) on hydrolysis give ortho-chloroanilines (10).Since the N-arylhydroxylamines are obtained from nitroarenes by partial reduction, the overall reaction amounts to the preparation of 10 from nitroarenes.