102862-46-4

Usage

Uses

Used in Organic Synthesis:
2,2-Oxiranedicarbonitrile, 3-(4-methylphenyl)is used as a key intermediate in the synthesis of a wide range of organic compounds. Its reactivity allows for the creation of complex molecules that are essential in various chemical processes.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2,2-Oxiranedicarbonitrile, 3-(4-methylphenyl)is utilized as a building block for the development of new drugs. Its structural properties make it a promising candidate for the creation of novel therapeutic agents.
Used in Polymer and Material Science:
2,2-Oxiranedicarbonitrile, 3-(4-methylphenyl)is also used as a starting material in the synthesis of new polymers and materials. Its potential applications in this field are currently being explored, with the aim of developing innovative products with improved properties.
Used in Research and Development:
2,2-Oxiranedicarbonitrile, 3-(4-methylphenyl)is employed in research settings to study its biological activities and toxicological properties. This information is crucial for understanding its potential applications and safety in various industries.

Upstream product

• 2826-25-7 2-(4-methylbenzylidene)malononitrile 
• 104-87-0 4-methyl-benzaldehyde 
• 109-77-3 malononitrile 

Downstream Products

• 42419-53-4 morpholin-4-yl-p-tolyl-acetonitrile 
• 102862-28-2 3-p-Tolyl-imidazo[1,2-a]pyrimidin-2-ol 
• 10399-09-4 4-Methyl-α-methoxy-phenylessigsaeure-methylester 
• 103807-51-8 methyl (±)-2-fluoro-2-(p-tolyl)acetate 
• 127895-03-8 2H-(p-tolyl)-imidazo<1,2-b>thiazole-3,6-dione 
• 127895-08-3 3-[3H-Benzooxazol-(2E)-ylidene]-2-oxo-3-p-tolyl-propionitrile 
• 15674-78-9 (+/-)-α-bromo-p-tolylacetic acid ethyl ester 
• 79309-66-3 ethoxy-p-tolyl-acetic acid ethyl ester 
• 103807-60-9 2-Chloro-N-(2-hydroxy-ethyl)-2-p-tolyl-acetamide 
• 110520-40-6 Chloro-p-tolyl-acetic acid N',N'-diphenyl-hydrazide 
• 102862-25-9 7-Methyl-3-p-tolyl-imidazo[1,2-a]pyridin-2-ol 
• 102862-38-4 2-Bromo-N-(4,5-dihydro-thiazol-2-yl)-2-p-tolyl-acetamide 
• 102862-42-0 2-Chloro-N-(4,5-dihydro-thiazol-2-yl)-2-p-tolyl-acetamide 
• 110520-39-3 Acetic acid N'-(2-bromo-2-p-tolyl-acetyl)-hydrazide 

Relevant academic research and scientific papers

Ultrasound-assisted rapid synthesis of β-cyanoepoxides using hypervalent iodine reagents

An elegant approach for the rapid synthesis of β-cyanoepoxides 3 by the epoxidation of β-cyanostyrenes 1 with PIDA 2a is described. The epoxidation of β-cyanostyrenes 1 was performed with 1.2 equiv. of PIDA 2a in MeCN-H2O (1:1) at room temperature in ultrasonic bath. The epoxidation reactions were completed in short reaction time and β-cyanoepoxides 3 were isolated in 69–94% yields.

Hypervalent Iodine(III)-Catalyzed Epoxidation of β-Cyanostyrenes

A convenient approach for the synthesis of β-cyanoepoxides is illustrated by iodine(III)-catalyzed epoxidation of electron-deficient β-cyanostyrenes, wherein the active catalytic iodine(III) species was generated in situ. The epoxidation of β-cyanostyrenes was performed using 10 molpercent PhI as precatalyst in the presence of 2.0 equivalents Oxone as an oxidant and 2.4 equivalents of TFA as an additive at room temperature under ultrasonic radiations. The β-cyanoepoxides were isolated in good to excellent yields in a short reaction time.

Access to thiomorpholin-3-one derivatives: [3 + 3]-cycloadditions of α-chlorohydroxamates and 1,4-dithiane-2,5-diol

A protocol of [3 + 3]-cycloaddition was proposed for the synthesis of 2H-1,4-thiazin-3(4H)-ones and thiomorpholine-3,5-diones from α-chlorohydroxamates and 1,4-dithiane-2,5-diol. This direct and practical method provides a novel and rapid approach for the

Epoxidation of vinyl cyanides by calcium hypochlorite under catalyst- and solvent-free conditions

In this paper, epoxidation of a wide range of alkenes by calcium hypochlorite (Ca(OCl)2) was investigated under catalyst- and solvent-free conditions. It was noticed that the highest yield was achieved with crushing, when the reaction was betwe

Chemoenzymatic Synthesis of α-Cyano Epoxides by a Tandem-Knoevenagel-Epoxidation Reaction

An efficient lipase-mediated synthesis of α-cyano epoxides through a tandem-Knoevenagel-epoxidation reaction was explored for the first time. This method provides a green, mild, and convenient route for the synthesis of α-cyano epoxides; moreover, the app

Synthesis, characterization and mass spectrometric fragmentation of gem-dicyanooxiranes derived from benzylidene malononitrile

Benzylidene Malononitriles react with calcium hypochlorite in carbon tetrachloride at room temperature to afford substituted phenyl-1,1′-dicyanooxiranes, a class of important synthetic intermediates. The structure of these phenyl gem-dicyanooxiranes have

Facile Epoxidation of Alumina-Supported Electrophilic Alkenes and Montmorillonite-Supported Electrophilic Alkenes with Sodium Hypochlorite

Alkenes gem-substituted by two electron-withdrawing substituents, dispersed on alumina or montmorillonite, are conveniently epoxided by sodium hypochlorite.A mixture of aldehyde and methylcyanoacetate or malononitrile, treated with alumina and sodium hypo

SYNTHESES D'ESTERS OU D'ACIDES α-HALOGENES A PARTIR DES GEM DICYANO EPOXIDES.

α-halogeno esters or α-halogenoacids were easily prepared by selective one pot reaction of gem-dicyano epoxides with halohydric acids in an alcoholic or aqueous media.