79309-66-3Relevant academic research and scientific papers
HYPERVALENT IODINE IN ORGANIC SYNTHESIS. A NEW ROUTE TO α-FUNCTIONALIZED CARBOXYLATE ESTERS.
Moriarty, Robert M.,Hu, Henry
, p. 2747 - 2750 (1981)
Aryl and alkylcarboxylate esters are converted into the corresponding α-hydroxy acids or α-alkoxyesters upon treatment with C6H5I(OAc)2 and base in the appropriate solvent.
A facile one-pot synthesis of α-hydroxy acids and their derivatives
Florac,Le Grel,Baudy-Floc'h,Robert
, p. 741 - 743 (2007/10/02)
2-Substituted oxirane-1,1-dicarbonitriles react with water, alcohols or phenol to give 2-substituted 2-hydroxyacetic acids, alkyl-2-alkoxyacetates and phenyl 2-phenoxyacetates, respectively. Reaction of 2-substituted oxirane-1,1-dicarbonitrile with thiophenol and a nucleophile, typically water ethanol or urea, gave 2-(phenylthio)acetic acids, ethyl 2-(phenylthio)acetates and N-aminocarbonyl-2-(phenylthio)acetamides.
