3158-73-4

Basic information

• Product Name: 2-cyclopropylaniline
• Synonyms: 2-Cyclopropylbenzenamine;(2-cyclopropylphenyl)amine(SALTDATA: FREE)
• CAS NO: 3158-73-4
• Molecular Formula: C₉H₁₁N
• Molecular Weight: 133.19
• EINECS: 221-600-0
• Mol File: 3158-73-4.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 221.8 °C at 760 mmHg
• Flash Point: 94.5 °C
• Appearance: /
• Density: 1.112 g/cm³
• Vapor Pressure: 0.105mmHg at 25°C
• Refractive Index: 1.628
• Storage Temp.: 2-8°C
• PKA: 4.15±0.10(Predicted)
• CAS DataBase Reference: 2-cyclopropylaniline(CAS DataBase Reference)
• NIST Chemistry Reference: 2-cyclopropylaniline(3158-73-4)
• EPA Substance Registry System: 2-cyclopropylaniline(3158-73-4)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 3158-73-4(Hazardous Substances Data)

Usage

General Description

2-Cyclopropylaniline is a chemical compound with the molecular formula C9H11N. It is an aromatic amine with a cyclopropyl group attached to the aniline ring. 2-cyclopropylaniline is used as an intermediate in the synthesis of pharmaceuticals, dyes, and other important organic compounds. It is also used as a building block for the preparation of various heterocyclic compounds. 2-Cyclopropylaniline has potential applications in the field of medicinal chemistry, specifically in the development of new drugs and pharmaceuticals. It is important to handle this chemical with care, as it can be hazardous if not handled properly.

InChI:InChI=1/C9H11N/c10-9-4-2-1-3-8(9)7-5-6-7/h1-4,7H,5-6,10H2

Upstream product

• 577-19-5 2-nitrophenyl bromide 
• 41009-82-9 o-dicyclopropylbenzene 
• 41010-17-7 1,4-dicyclopropylbenzene 
• 35896-11-8 1,3-dicyclopropylbenzene 
• 873-49-4 cyclopropylbenzene 
• 10292-65-6 2-nitrophenylcyclopropane 

Downstream Products

• 345894-03-3 N-(4-nitrobenzylidene)-2-cyclopropylaniline 
• 368890-80-6 N-(4-methylbenzoyl)-2-cyclopropylaniline 
• 199296-64-5 (3-cyclopropyl-2-hydroxyphenyl)-(1-methyl-5-nitro-1H-2-imidazolyl)methanol 
• 1221566-65-9 C₂₁H₂₄N₂O 
• 1421620-30-5 2,4-dichloro-6-cyclopropylaniline 
• 1421620-54-3 2,4-dichloro-6-cyclopropylphenylacetic acid 
• 1421620-37-2 2,4-dichloro-6-cyclopropylphenylacetic acid methyl ester 
• 1417885-67-6 N-((2-cyclopropylphenyl)carbamothioyl)benzamide 
• 1417885-77-8 1-(2-cyclopropylphenyl)thiourea 

Relevant articles and documents

Cu(II)-Mediated N-H and N-Alkyl Aryl Amination and Olefin Aziridination

Cu(II)-mediated direct NH2 and NH alkyl aryl aminations and olefin aziridinations are described. These room-temperature, one-pot, environmentally friendly procedures replace costly Rh2 catalysts and, in some instances, display important differences with comparable Rh2- and Fe-supported reactions.

SUBSTITUTED TRICYCLIC COMPOUNDS WITH ACTIVITY TOWARDS EP1 RECEPTORS

The present invention belongs to the field of EP1 receptor ligands. More specifically it refers to compounds of general formula (I) having great affinity and selectivity for the EP1 receptor. The invention also refers to the process for their preparation, to their use as medicament for the treatment and/or prophylaxis of diseases or disorders mediated by the EP1 receptor as well as to pharmaceutical compositions comprising them.

Aminopyrroline compounds

Compound of formula (I): in which: n is 1 or 2, X represents alkylene, alkenylene, alkynylene or optionally substituted arylene or heteroarylene, R10represents hydrogen or alkyl and R11and R12together form a bond, or alternatively R12represents hydrogen or alkyl and R10and R11together form a bond, R2, R3and R4each independently of the others represents hydrogen, alkyl, hydroxyalkyl, alkoxy, alkoxycarbonyl, aryl, arylalkyl or aryloxyalkyl, or two of R2, R3and R4form a cycloalkyl radical. Medicinal products containing the same are useful in the treatment of cardiovascular diseases.