10320-59-9

Basic information

• Product Name: 6-chloro-1-methylquinazoline-2,4(1H,3H)-dione
• CAS NO: 10320-59-9
• Molecular Formula: C₉H₇ClN₂O₂
• Molecular Weight: 210.6171
• Mol File: 10320-59-9.mol
• Article Data: 2

Chemical Properties

• Density: 1.42g/cm³
• Refractive Index: 1.597
• CAS DataBase Reference: 6-chloro-1-methylquinazoline-2,4(1H,3H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 6-chloro-1-methylquinazoline-2,4(1H,3H)-dione(10320-59-9)
• EPA Substance Registry System: 6-chloro-1-methylquinazoline-2,4(1H,3H)-dione(10320-59-9)

Safety Data

• Hazardous Substances Data: 10320-59-9(Hazardous Substances Data)

Usage

General Description

6-chloro-1-methylquinazoline-2,4(1H,3H)-dione is a chemical compound with the molecular formula C9H7ClN2O2. It is a quinazoline derivative with a chlorine atom and a methyl group attached to the quinazoline ring. 6-chloro-1-methylquinazoline-2,4(1H,3H)-dione is of interest in pharmaceutical research due to its potential biological activities, particularly as a potential drug candidate for the treatment of various diseases. Its specific properties and potential applications are still being investigated, and it may have diverse uses in the fields of medicine and chemical synthesis.

Upstream product

• 55150-07-7 5-chloro-2-methylaminobenzoic acid methyl ester 
• 85-91-6 Methyl N-methylanthranilate 
• 134-20-3 2-carbomethoxyaniline 
• 57-13-6 urea 
• 33280-14-7 5-chloro-2-methylamino-benzoic acid 
• 18437-66-6 N-(t-butoxycarbonyl)-4-chloroaniline 
• 207735-50-0 3-(tert-butyl)-6-chloroquinazoline-2,4(1H,3H)-dione 
• 889849-94-9 3-tert-butyl-6-chloro-1-methyl-1H-quinazoline-2,4-dione 

Relevant articles and documents

Acetylhydrazone-based compounds and preparation method thereof

The invention discloses acetylhydrazone-based compounds and a preparation method thereof. The acetylhydrazone-based compounds are 2-(1-methyl-6-chloro-2,4 (1H, 3H)-quinazolinedione) acetylhydrazone-based compounds expressed by a general formula I. In-vitro antimicrobial activity tests find that the acetylhydrazone-based compounds have certain inhibitory activity on gram-positive bacteria (staphylococcus aureus, methicillin-resistant staphylococcus aureus and bacillus subtilis), gram-negative bacteria (escherichia coli, proteusbacillus vulgaris and pseudomonas aeruginosa), and fungi (candida albicans, aspergillus flavus, aspergillus fumigatus and cryptococcus neoformans), and some compounds have the inhibitory activity on some tested strains that is close and even prior to the inhibitory activity of the existing drug streptomycin sulfate polyoxin B, so that the compounds can be used for preparing antibacterial and/or antifungal drugs. The preparation method for the compounds is simple, the raw materials are easily available, and the cost is relatively low.