103291-08-3

Upstream product

• 79601-21-1 3-(3-methoxyphenylpiperidine) 
• 19725-18-9 (+)-3-(3-methoxyphenyl)piperidine hydrochloride 
• 626-55-1 3-Bromopyridine 
• 36282-40-3 (3-methoxyphenyl)magnesium bromide 
• 4373-67-5 3-(3-methoxyphenyl)pyridine 

Downstream Products

• 147161-50-0 (R)-N-cyanomethyl-3-(3-methoxyphenyl)piperidine 
• 79601-41-5 1-[(R)-3-(3-Methoxy-phenyl)-piperidin-1-yl]-propan-1-one 
• 1602922-47-3 (4-chlorophenyl)-carbamic acid (S)-2,2,2-trifluoro-1-[(R)-3-(3-methoxyphenyl)-piperidin-1-ylmethyl]-ethyl ester hydrochloride 
• 1602923-81-8 (S)-1,1,1-trifluoro-3-((R)-3-(3-methoxyphenyl)piperidin-1-yl)propan-2-ol 
• 147161-62-4 (R)-N-propyl-3-(3-methoxy-4-nitrophenyl)piperidine 
• 147161-64-6 (R)-N-propyl-3-(3-methoxy-4-aminophenyl)piperidine 
• 91110-04-2 (3S)-(-)-3-(3-methoxyphenyl)-1-propylpiperidine 
• 85976-54-1 (+)-preclamol 

Relevant academic research and scientific papers

CHIRAL, POTENTIALLY IRREVERSIBLE LIGANDS FOR THE SIGMA RECEPTOR BASED ON THE STRUCTURE OF 3-(3-HYDROXYPHENYL)-N-PROPYLPIPERIDINE (3-PPP)

(+)-3-PPP is an optically active, highly potent and selective ligand for sigma receptors.The resolved enantiomeric pairs of potential irreversible sigma ligands (5a,b) and (9a,b) were designed and synthesized based on the structure of 3-PPP.An improved me

1,3-disubstituted piperidine compounds as neuroleptic agents

Certain novel 1-(substituted-alkyl)-3-(3-hydroxyphenyl)piperidine compounds, and the pharmaceutically-acceptable acid-addition salts thereof, possess pharmaceutical activity as neuroleptic agents, and they are useful for treating psychotic disorders, e.g.

Resolved 3-(3-Hydroxyphenyl)-N-n-propylpiperidine and Its Analogues: Central Dopamine Receptor Activity

Seven enantiomeric pairs of N-alkyl analogues of 3-(3-hydroxyphenyl)-N-n-propylpiperidine (3-PPP, 12) have been synthesized and evaluated pharmacologically (biochemistry and behavior) in order to examine their ability to interact with central dopamine (DA