103440-35-3Relevant articles and documents
Grignard reactions in imidazolium ionic liquids
Handy, Scott T.
, p. 4659 - 4662 (2006)
A new, base-stable, imidazolium room-temperature ionic liquid (RTIL) has been prepared and applied to the addition of Grignard reagents to carbonyl compounds. These reactions occur readily at ambient temperature to afford the alcohol products in good to excellent yield. The RTIL can be recycled and reused numerous times without any difficulty.
Donor–Acceptor Complex Enables Alkoxyl Radical Generation for Metal-Free C(sp3)–C(sp3) Cleavage and Allylation/Alkenylation
Zhang, Jing,Li, Yang,Xu, Ruoyu,Chen, Yiyun
supporting information, p. 12619 - 12623 (2017/09/11)
The alkoxyl radical is an essential and prevalent reactive intermediate for chemical and biological studies. Here we report the first donor–acceptor complex-enabled alkoxyl radical generation under metal-free reaction conditions induced by visible light. Hantzsch ester forms the key donor–acceptor complex with N-alkoxyl derivatives, which is elucidated by a series of spectrometry and mechanistic experiments. Selective C(sp3)-C(sp3) bond cleavage and allylation/alkenylation is demonstrated for the first time using this photocatalyst-free approach with linear primary, secondary, and tertiary alkoxyl radicals.
Methylaluminum bis(4-substituted-2,6-di-tert-butylphenoxide) as an efficient nonchelating Lewis acid: Application to asymmetric Diels-Alder reaction and diastereoselective alkylation to alkoxy carbonyl substrates
Maruoka, Keiji,Oishi, Masataka,Shiohara, Kei,Yamamoto, Hisashi
, p. 8983 - 8996 (2007/10/02)
The exceptionally bulky methylaluminum bis(4-substituted-2,6-di-tert-butylphenoxide) such as MAD or MABR can be successfully utilized as a highly efficient nonchelating Lewis acid for achieving high stereoselectivity in 1,n asymmetric induction in cyclic
Preparation of benzyl ketones
-
, (2008/06/13)
Benzyl ketones of the general formula I STR1 where R1 is C1 -C8 -alkyl which is unsubstituted or substituted by cycloalkyl or aryl and R2 and R3 are each halogen, C1 -C4 -alkyl, hydroxyl, C1 -C4 -alkoxy or C2 -C4 -methylenedioxy, are prepared by a process in which a glycol monoether of the general formula II STR2 where R1, R2 and R3 have the abovementioned meanings and R4 is C1 -C8 -alkyl, is converted in the presence of silica, a phosphate or a zeolite at from 50° to 500° C. and under from 0.01 to 50 bar.
Elaboration of α-Substituted Benzyl Ethers and Sulphides by Suppression of the Wittig and Related Rearrangements
Davies, Stephen G.,Holman, Nicholas J.,Laughton, Charles A.,Mobbs, Bryan E.
, p. 1316 - 1317 (2007/10/02)
Co-ordination of benzyl alkyl ethers and sulphides to chromium tricarbonyl allows α-substitution via the corresponding α-carbanions to be achieved by suppression of the Wittig and related rearrangements.
