1036378-89-8

Basic information

• Product Name: N-(4-BroMobenzyl)-2,2-diMethoxyethylaMine
• Synonyms: N-(4-broMobenzyl)-2,2-diMethoxyethaN/AMine;N-(4-BroMobenzyl)-2,2-diMethoxyethylaMine
• CAS NO: 1036378-89-8
• Molecular Formula: C₁₁H₁₆BrNO₂
• Molecular Weight: 274.15424
• Mol File: 1036378-89-8.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-(4-BroMobenzyl)-2,2-diMethoxyethylaMine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-BroMobenzyl)-2,2-diMethoxyethylaMine(1036378-89-8)
• EPA Substance Registry System: N-(4-BroMobenzyl)-2,2-diMethoxyethylaMine(1036378-89-8)

Safety Data

• Hazardous Substances Data: 1036378-89-8(Hazardous Substances Data)

Usage

Description

N-(4-Bromobenzyl)-2,2-dimethoxyethylamine, a chemical compound with the molecular formula C11H16BrNO2, is an amine derivative featuring a benzyl group and two methoxyethyl groups. It is widely recognized for its role in organic synthesis and medicinal chemistry, serving as a fundamental building block for the creation of various pharmaceuticals and biologically active compounds. Its potential in the development of new drugs and its utility as a reagent in chemical research and development are noteworthy. However, it is crucial to handle this compound with caution due to potential health and safety risks if not used properly.

Uses

Used in Pharmaceutical Industry:
N-(4-Bromobenzyl)-2,2-dimethoxyethylamine is used as a key intermediate in the synthesis of pharmaceuticals for its ability to contribute to the development of new drugs. Its unique structure allows for the creation of a variety of biologically active compounds, enhancing the range of treatments available in the medical field.
Used in Organic Synthesis:
In the realm of organic synthesis, N-(4-Bromobenzyl)-2,2-dimethoxyethylamine is utilized as a versatile building block, enabling the construction of complex organic molecules. Its presence in the synthesis process can lead to the formation of compounds with specific properties, making it a valuable asset in the synthesis of specialty chemicals.
Used in Medicinal Chemistry Research:
N-(4-Bromobenzyl)-2,2-dimethoxyethylamine is employed as a reagent in medicinal chemistry research to explore its potential in the discovery of new therapeutic agents. Its structural features make it a candidate for further modification and optimization in the quest for more effective and safer medications.
Used in Chemical Research and Development:
N-(4-BroMobenzyl)-2,2-diMethoxyethylaMine is also used in chemical research and development as a reagent, facilitating the advancement of chemical knowledge and the creation of innovative chemical processes. Its role in this context is to support the exploration of new chemical reactions and the synthesis of novel compounds with potential applications across various industries.

Upstream product

• 1122-91-4 4-bromo-benzaldehyde 
• 22483-09-6 2,2-dimethoxyethylamine 
• 1009309-65-2 dimethyl(p-bromobenzylidene)aminoacetal 

Downstream Products

• 1036378-91-2 N-(4-bromo-benzyl)-N-(2,2-dimethoxy-ethyl)-4-methyl-benzenesulfonamide 
• 494833-86-2 6-bromo-2-tosyl-1,2,3,4-tetrahydroisoquinoline 
• 34784-05-9 6-bromo-isoquinoline 
• 105764-01-0 1-(4-Bromo-benzyl)-1,3-dihydro-imidazole-2-thione 

Relevant articles and documents

Synthesis of tetrahydroisoquinolines through TiCl4-mediated cyclization and Et3SiH reduction

A versatile and efficient telescoped reaction sequence for the synthesis of tetrahydroisoquinolines (THIQs) is reported that uses TiCl4 to promote cyclization of a benzylaminoacetal derivative and Et3SiH for reduction of the intermediate 4-hydroxy-THIQ. This method is complimentary to the classical Pomeranz-Fritsch and related reactions since it tolerates electron-withdrawing substituents and allows access to 8-substituted THIQs.

ARYL CARBOXAMIDE DERIVATIVES AS SODIUM CHANNEL INHIBITORS FOR TREATMENT OF PAIN

The present invention provides compounds that are inhibitors of voltage-gated sodium channels (Nav), in particular Nav 1.7, and are therefore useful for the treatment of diseases treatable by inhibition of these channels, in particular, chronic pain disorders. Also provided are pharmaceutical compositions containing such compounds and processes for preparing such compounds.

SUBSTITUTED ISOQUINOLINE AND ISOQUINOLINONE DERIVATIVES

The invention relates to 6-substituted isoquinoline and isochinolone derivatives of the formula (I) useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds.