1036637-32-7

Basic information

• Product Name: methyl (1S,2R)-1-nitro-2-phenylcyclopropanecarboxylate
• Synonyms: methyl (1S,2R)-1-nitro-2-phenylcyclopropanecarboxylate
• CAS NO: 1036637-32-7
• Molecular Weight: 221.213
• Mol File: 1036637-32-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl (1S,2R)-1-nitro-2-phenylcyclopropanecarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl (1S,2R)-1-nitro-2-phenylcyclopropanecarboxylate(1036637-32-7)
• EPA Substance Registry System: methyl (1S,2R)-1-nitro-2-phenylcyclopropanecarboxylate(1036637-32-7)

Safety Data

• Hazardous Substances Data: 1036637-32-7(Hazardous Substances Data)

Upstream product

• 100-42-5 styrene 
• 2483-57-0 methyl 2-nitroacetate 

Downstream Products

• 1379337-81-1 C₁₁H₁₃NO₂ 
• 123806-65-5 methyl (1S,2R)-1-amino-2-phenylcyclopropanecarboxylate 
• 123806-63-3 methyl (1R,2S)-1-amino-2-phenylcyclopropanecarboxylate 
• 54-97-7 1-amino-2-phenylcyclopropane 
• 1379337-81-1 C₁₁H₁₃NO₂ 
• 1374241-52-7 C₁₈H₁₇NO₃ 
• 1374241-55-0 C₁₈H₁₇NO₃ 
• 50584-02-6 trans-2-Benzamido-1-phenyl-cyclopropan 
• 95-62-5 (1R,2S)-1-amino-2-phenylcyclopropane 
• 3721-28-6 (1S,2R)-tranylcypromine 
• 874341-82-9 [(1S,2R)-2-nitrocyclopropyl]benzene 
• 110769-86-3 (Z)-2,3-methanophenylalanine methyl ester 
• 110769-84-1 methyl (1R,2R)-1-amino-2-phenylcyclopropanecarboxylate 
• 1095278-82-2 methyl (1S,2S)-1-nitro-2-phenylcyclopropanecarboxylate 

Relevant articles and documents

Catalytic asymmetric synthesis of nitrocyclopropane carboxylates

A Cu(I)-catalyzed asymmetric cyclopropanation of alkenes with an iodonium ylide has been developed. The copper source, hypervalent iodine source, solvent, and additives all have a significant effect on the yields and enantioselectivities. High enantioselectivity (up to 99:1 er) and diastereoselectivity (95:5 dr trans/cis) were achieved for a wide range of alkenes. Conditions were developed to convert the trans products to the cis isomers. In addition, 1-nitrocyclopropyl carboxylates were transformed into the corresponding substituted cyclopropane amino acids and aminocyclopropanes. Moreover, a comparative study between Zn- and In-mediated reduction reactions of the nitro group in these compounds with regards to the er erosion in the process is also documented.