1037-20-3 Usage
General Description
1-(2-phenoxyethyl)-4-phenyl-piperazine, also known as phenoxyethopiperazine, is a chemical compound that belongs to the class of piperazines. It is a psychoactive drug that has been studied for its potential use in treating anxiety and depression. It acts as a serotonin receptor antagonist and has been shown to have anxiolytic and antidepressant properties in animal studies. However, little is known about its specific mechanisms of action and potential side effects. More research is needed to determine its safety and efficacy for therapeutic use in humans.
Check Digit Verification of cas no
The CAS Registry Mumber 1037-20-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,0,3 and 7 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1037-20:
(6*1)+(5*0)+(4*3)+(3*7)+(2*2)+(1*0)=43
43 % 10 = 3
So 1037-20-3 is a valid CAS Registry Number.
InChI:InChI=1/C18H22N2O/c1-3-7-17(8-4-1)20-13-11-19(12-14-20)15-16-21-18-9-5-2-6-10-18/h1-10H,11-16H2
1037-20-3Relevant articles and documents
N-Arylation of DABCO with Diaryliodonium Salts: General Synthesis of N-Aryl-DABCO Salts as Precursors for 1,4-Disubstituted Piperazines
Bugaenko, Dmitry I.,Yurovskaya, Marina A.,Karchava, Alexander V.
, p. 6389 - 6393 (2018/10/09)
Employing DABCO as a substrate, aryl(mesityl)iodonium triflates are introduced as arylating agents for a tertiary sp3-nitrogen. Mild conditions and exceptional selectivity of the aryl group transfer allow unprecedented N-aryl-DABCO salts to be obtained, bearing substituents of different electronic natures. This metal-free methodology has no analogy among known transition-metal-based reactions. The utility of isolated N-aryl-DABCO salts is demonstrated for the preparation of flibanserin.
