103767-90-4Relevant academic research and scientific papers
Synthesis and pharmacological investigations of novel 2-phenylquinazolin-4(3H)-one derivatives
Saravanan, Govindaraj,Alagarsamy, Veerachamy,Kumar, Pandurangan Dinesh
, p. 408 - 422 (2015)
A series of novel 2-phenyl-3-(4-(5-substitutedphenylisoxazol-3-yl)phenyl)quinazolin-4(3H)-one 5a-5o were designed and synthesized from anthranilic acid. All the synthesized compounds were characterized by FT-IR, 1H NMR, mass spectroscopy, and b
Synthesis and biological evaluation of some anthranilic acid and 2-phenylquinazoline-4(3H)-one analogues
Banerjee, Mrityunjay,Behera, Chinmoy C.,Pradhan, Guru C.,Azam, M. Afzal,Sahu, Susant K.
experimental part, p. 134 - 142 (2010/08/07)
In the present investigation a novel series of N-(phenyl) chalconyl anthranilic acids containing pyrazolines (4a-j), tetra- hydropyrimidines (4k-o), tetrahydrothiopyrimidines (4p-t) and 2-phenylquinazolin-4(3iJ)-ones containing pyrazolines (8a-f), isoxazolines (8g-l), tetrahydropyrimidines (8m-r) and tetrahydrothiopyrimidines (8s-x) were synthesized and characterized by elemental analysis, FT-IR, 1H NMR and mass spectroscopy. The title compounds (4a-t) and (8a-x) were investigated for their analgesic, anti-inflammatory, antimicrobial and in vitro protein denaturation activities. Compounds 4j and 8x were identified as lead compounds with optimum analgesic, anti-inflammatory and antimicrobial activities.
