1037795-38-2

Upstream product

• 133174-15-9 (S)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-5-ureidopentanoic acid 
• 18144-47-3 tert-butyl 4-aminobenzoate 
• 72080-83-2 2-benzyloxycarbonylaminoethylamine 
• 1037795-30-4 C₃₇H₄₅N₅O₇ 
• 932744-52-0 C₃₂H₃₆N₄O₆ 
• 1037794-82-3 C₁₇H₂₆N₄O₄ 
• 1027359-36-9 N-(2-benzyloxycarbonylaminoethyl)bromoacetamide 
• 1037795-34-8 Boc-L-valine-L-citrulline-p-aminobenzoic acid t-butyl ester 

Downstream Products

• 1037795-42-8 C₃₀H₄₁N₇O₈ 

Relevant academic research and scientific papers

CHEMICAL LINKERS AND CLEAVABLE SUBSTRATES AND CONJUGATES THEREOF

The present disclosure provides drug-ligand conjugates and drug-cleavable substrate conjugates that are potent cytotoxins. The disclosure is also directed to compositions containing the drug-ligand conjugates, and to methods of treatment using them.

CHEMICAL LINKERS WITH SINGLE AMINO ACIDS AND CONJUGATES THEREOF

The present disclosure provides drug-ligand conjugates that are potent cytotoxins and include a linker between the drug and ligand where the linker has a single amino acid. The disclosure is also directed to compositions containing the drug-ligand conjugates, and to methods of treatment using them.