10381-70-1

Basic information

• Product Name: 1-(benzylsulfinyl)-4-methylbenzene
• Synonyms: 1-(Benzylsulfinyl)-4-methylbenzene; benzene, 1-methyl-4-[(phenylmethyl)sulfinyl]-; Benzyl 4-methylphenyl sulfoxide; Benzyl(4-methylphenyl)sulfoniumolate; sulfonium, hydroxy(4-methylphenyl)(phenylmethyl)-, inner salt
• CAS NO: 10381-70-1
• Molecular Formula: C₁₄H₁₄OS
• Molecular Weight: 230.3254
• Mol File: 10381-70-1.mol
• Article Data: 97

Chemical Properties

• Boiling Point: 405.4°C at 760 mmHg
• Flash Point: 199°C
• Density: 1.19g/cm³
• Vapor Pressure: 2.05E-06mmHg at 25°C
• Refractive Index: 1.639
• CAS DataBase Reference: 1-(benzylsulfinyl)-4-methylbenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(benzylsulfinyl)-4-methylbenzene(10381-70-1)
• EPA Substance Registry System: 1-(benzylsulfinyl)-4-methylbenzene(10381-70-1)

Safety Data

• Hazardous Substances Data: 10381-70-1(Hazardous Substances Data)

Usage

General Description

1-(benzylsulfinyl)-4-methylbenzene is a chemical compound with the molecular formula C15H14OS. It is a organic compound that contains a benzene ring with a methyl group and a sulfinyl group attached to it, through a benzyl linkage. The compound has potential applications in organic synthesis and pharmaceutical research, due to its unique structure and reactivity. It is important to handle this chemical with caution, as it may have potential hazards and safety concerns associated with its handling and use. Overall, 1-(benzylsulfinyl)-4-methylbenzene is a versatile compound with interesting properties that may have various applications in chemical and pharmaceutical industries.

Upstream product

• 2943-42-2 di(4-methyl)phenylthiosulfonate 
• 6921-34-2 benzylmagnesium chloride 
• 5023-60-9 1-benzylsulfanyl-4-methyl-benzene 
• 100-39-0 benzyl bromide 
• 921765-53-9 3-(phenylmethylsulfinyl)propionic acid tert-butyl ester 
• 624-31-7 4-tolyl iodide 
• 106-45-6 para-thiocresol 
• 109-72-8 n-butyllithium 
• 184377-59-1 E-2-carbomethoxyethenyl p-tolyl sulfoxide 
• 1569-69-3 Cyclohexanethiol 
• 124-41-4 sodium methylate 
• 4294-57-9 para-methylphenylmagnesium bromide 
• 100-44-7 benzyl chloride 
• 1517-82-4 (-)-menthyl p-toluenesulfinate 

Downstream Products

• 51774-54-0 Benzyl-p-tolylsulfoximin 
• 129161-98-4 (3S,4R)-3-Methyl-4-phenyl-4-(toluene-4-sulfinyl)-butyric acid methyl ester 
• 5023-60-9 1-benzylsulfanyl-4-methyl-benzene 
• 304690-05-9 benzyl p-tolyl sulfoxide 
• 4820-08-0 (R)-1-(benzylsulfinyl)-4-methylbenzene 
• 86448-74-0 (R)-1,2-Diphenyl-2-((S)-toluene-4-sulfinyl)-ethanone 
• 104891-19-2 (R)-3-Chloro-1-phenyl-1-((R)-toluene-4-sulfinyl)-propan-2-one 
• 104891-16-9 (S)-3-Chloro-1-phenyl-1-((R)-toluene-4-sulfinyl)-propan-2-one 
• 189396-88-1 (4-Methoxy-phenyl)-{(S)-2,2,2-trifluoro-1-[(S)-phenyl-((R)-toluene-4-sulfinyl)-methyl]-ethyl}-amine 

Relevant articles and documents

Cyanuric chloride promoted oxidation of sulfides to sulfoxides or sulfones in the presence of hydrogen peroxide

Aromatic and aliphatic sulfides are readily oxidized to sulfoxides or sulfones in high yield with 35% hydrogen peroxide in the presence of cyanuric chloride (CC) as an efficient activator. The oxidation of sulfides proceeds at room temperature and the corresponding sulfoxides or sulfones was selectively obtained by controlling the amounts of H2O2 and CC. Various sulfides possessing functional groups such as hydroxyl, methoxy, nitrile, aldehyde and olefinic double bond were successfully and selectively oxidized without affecting sensitive functionalities. [image omitted].

Selective oxidation of sulfides to sulfoxides catalysed by deep eutectic solvent with H2O2

A Bronsted acidic deep eutectic solvent based on choline chloride and p-toluenesulfonic acid (ChCl/p-TsOH, 1 : 1) was prepared and utilised for the selective oxidation of sulfides with H2O2 as the oxidant. Broad substrate compatibili

A multifunctional Co-based metal-organic framework: heterogeneous catalysis, chemiluminescence sensing and moisture-dependent solvatochromism

Crystalline materials with multi-catalytic applications are of great value to both fundamental research and practical applications. The platform of metal-organic frameworks (MOFs) is utilized to fabricate a microporous versatile catalyst with high stability. Self-assembly of a flexible ligand, 4-(4-carboxybenzylamino)benzoic acid (H2CBBA), with Co(ii) resulted in a 3D framework, CBBA-Co, with Co3O clusters exposed in the zigzag channels. Upon in situ activation, CBBA-Co exhibited multiple heterogeneous catalytic activities. Theoretical calculations were carried out to give insights into the catalytic process. In addition, CBBA-Co also showed promising potential in optical sensing by virtue of its catalytic activity. The luminol chemiluminescence was greatly enhanced by CBBA-Co, and linear determination of the concentration of H2O2 in the range of 0-30% was established. The successful implementation of CBBA-Co indicates the feasibility and promising future of employing MOFs as an efficient platform for the fabrication and study of multifunctional catalysts, both experimentally and theoretically.

A SnIV-porphyrin-based metal-organic framework for the selective photo-oxygenation of phenol and sulfides

A functional tin(IV)-porphyrin derivative was used as a building block to construct a novel 3D porous metal-organic framework (MOF). The MOF is built up from tin(IV)-porphyrin struts linking up Zn atoms and formates joining Sn IV centers. The i

EFFICENT OXIDATION OF SULFIDES TO THE SULFOXIDES USING A NEW SULFINYLPEROXY INTERMEDIATE GENERATED FROM 2-NITROBENZENESULFINYL CHLORIDE AND SUPEROXIDE

Various sulfides were found to react with a sulfinylperoxy intermediate generated in situ by the treatment of 2-nitrobenzenesulfinyl chloride with superoxide at -25 deg C in acetonitrile to afford the corresponding sulfoxides selectively in excellent yields together with traceable amount of the sulfones under mild conditions.

The X-ray structures of sulfoxides

We have structurally characterized and investigated a range of sulfoxide compounds containing aryl and alkyl substituents. Compounds 1 and 3-6 all crystallize in an orthorhombic space group, where compounds 2 and 7 crystallize in a monoclinic space group.

Hydrogen-bonding catalysis: Mild and highly chemoselective oxidation of sulfides

N,N′-Bis[3,5-bis(trifluoromethyl)phenyl]thiourea, employed at only 1 mol% loading, was found to be a very effective catalyst for the oxidation of sulfides with tert-butyl hydroperoxide (TBHP), affording the sulfoxides in high yield, excellent chemoselecti

HIO3 in the presence of wet SiO2: A mild and efficient reagent for selective oxidation of sulfides to sulfoxides under solvent-free conditions

In the presence of wet SiO2, HIO3 is highly efficient for the selective oxidation of sulfides to sulfoxides. It may be applied to any type of dialkyl and alkyl aryl sulfides. It develops under solvent-free conditions, and gives high yield in the presence of different functional groups on the sulfide at room temperature.

Chiral Ligands in Hypervalent Iodine Compounds: Synthesis and Structures of Binaphthyl-Based λ3-Iodanes

Several novel binaphthyl-based chiral hypervalent iodine(III) reagents have been prepared and structurally analysed. Various asymmetric oxidative reactions were applied to evaluate the reactivities and stereoselectivities of those reagents. Moderate to excellent yields were observed; however, very low stereoselectivities were obtained. NMR experiments indicated that these reagents are very easily hydrolysed in either chloroform or DMSO solvents leading to the limited stereoselectivities. It is concluded that the use of chiral ligands is an unsuccessful way to prepare efficient stereoselective iodine(III) reagents.

Highly efficient and selective aqueous aerobic oxidation of sulfides to sulfoxides or sulfones catalyzed by tungstate-functionalized nanomaterial

A Br?nsted acidic ionic solid comrising tungstate-functionaized polyorganosiloxane framework (PMO-IL-WO42?) efficiently catalysed aerobic oxidation of sulfides in aqueous medium. The catalyst can selectively produce sulfoxides or sulfones by running the reaction at room temperature or 50 °C, respectively. Because of the ionic liquid-based charged surface containing hydrophobic organic functional groups and hydrophilic sulfonic acid group, the synergestic hydrophobic/hydrophilic and redox effect of PMO-IL-WO42- as water-friendly interfacial nanocatalyst simplifies and enhances the activity and selectivity toward the target sulfoxides or sulfones in water. Moreover, the PMO-IL-WO42- nanocatalyst exhibited outstanding stability and activity and can be recycled eight reaction runs without any significant activity and selectivity loss.