103844-17-3

Basic information

• Product Name: 2-(α-hydroxy-3',4',5'-trimethoxybenzyl)-3-(3'',4''-methylenedioxy-α-phenylthiobenzyl)-γ-butyrolactone
• CAS NO: 103844-17-3
• Molecular Weight: 524.592
• Mol File: 103844-17-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(α-hydroxy-3',4',5'-trimethoxybenzyl)-3-(3'',4''-methylenedioxy-α-phenylthiobenzyl)-γ-butyrolactone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(α-hydroxy-3',4',5'-trimethoxybenzyl)-3-(3'',4''-methylenedioxy-α-phenylthiobenzyl)-γ-butyrolactone(103844-17-3)
• EPA Substance Registry System: 2-(α-hydroxy-3',4',5'-trimethoxybenzyl)-3-(3'',4''-methylenedioxy-α-phenylthiobenzyl)-γ-butyrolactone(103844-17-3)

Safety Data

• Hazardous Substances Data: 103844-17-3(Hazardous Substances Data)

Upstream product

• 103844-15-1 (3,4-dioxymethylenephenyl)methyl phenyl sulfide 
• 497-23-4 2-buten-4-olide 
• 86-81-7 3,4,5-trimethoxy-benzaldehyde 
• 20850-43-5 5-(chloromethyl)-1,3-benzodioxole 
• 495-76-1 piperonol 

Downstream Products

• 477-51-0 rac-(7'β,8α,8'percentb)-3',4',5'-trimethoxy-4,5-methylenedioxy-2,7'-cyclolignan-9',9-olide 
• 103844-21-9 3-hydroxymethyl-6,7-methylenedioxy-4-phenylthio-1-(3',4',5'-trimethoxyphenyl)-1,2,3,4-tetrahydro-2-naphthoic acid γ-lactone 
• 103844-20-8 3-hydroxymethyl-5,6,7-trimethoxy-4-(3',4'-methylenedioxyphenyl)-1β-phenylthio-1,2,3,4-tetrahydro-2-naphthoic acid γ-lactone 
• 103844-20-8 3-hydroxymethyl-5,6,7-trimethoxy-4-(3',4'-methylenedioxyphenyl)-1α-phenylthio-1,2,3,4-tetrahydro-2-naphthoic acid γ-lactone 
• 17187-78-9 rac-(7'β,8β,8'α)-7-hydroxy-3',4',5'-trimethoxy-3,4-methylenedioxylignan-9',9-olides 

Relevant articles and documents

A SHORT VERSATILE SYNTHESIS OF ARYLTETRALIN LIGNANS INCLUDING DEOXYISOPODOPHYLLOTOXIN AND EPI-ISOPODOPHYLLOTOXIN

Cyclisation of tandem conjugate addition products (10), (15), and (20), prepared by reaction of anions derived from benzyl phenyl and benzyl t-butyl sulphides with but-2-en-4-olide, affords a series of aryltetralin lignans belonging to either the 'normal' or the 'retro' lactone series.Desulphurisation of compound (15) followed by cyclisation, or desulphurisation of the cyclised product (22b), affords deoxyisopodophyllotoxin (5), while treatment of compound (22b) with mercury(II) trifluoroacetate yields epi-isopodophyllotoxin (6).