17187-78-9

Basic information

• Product Name: (4R)-4-(1,3-benzodioxol-5-ylmethyl)-3-[(S)-hydroxy(3,4,5-trimethoxyphenyl)methyl]dihydrofuran-2(3H)-one
• CAS NO: 17187-78-9
• Molecular Formula: C₂₂H₂₄O₈
• Molecular Weight: 416.4212
• Mol File: 17187-78-9.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 610.4°C at 760 mmHg
• Flash Point: 212.7°C
• Density: 1.324g/cm³
• Vapor Pressure: 9.35E-16mmHg at 25°C
• Refractive Index: 1.591
• CAS DataBase Reference: (4R)-4-(1,3-benzodioxol-5-ylmethyl)-3-[(S)-hydroxy(3,4,5-trimethoxyphenyl)methyl]dihydrofuran-2(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: (4R)-4-(1,3-benzodioxol-5-ylmethyl)-3-[(S)-hydroxy(3,4,5-trimethoxyphenyl)methyl]dihydrofuran-2(3H)-one(17187-78-9)
• EPA Substance Registry System: (4R)-4-(1,3-benzodioxol-5-ylmethyl)-3-[(S)-hydroxy(3,4,5-trimethoxyphenyl)methyl]dihydrofuran-2(3H)-one(17187-78-9)

Safety Data

• Hazardous Substances Data: 17187-78-9(Hazardous Substances Data)

Usage

General Description

The chemical compound "(4R)-4-(1,3-benzodioxol-5-ylmethyl)-3-[(S)-hydroxy(3,4,5-trimethoxyphenyl)methyl]dihydrofuran-2(3H)-one" is a complex organic molecule with a dihydrofuran-2(3H)-one core structure. It contains a benzodioxol ring and a hydroxyphenyl group, and it has a chiral center, indicated by the "R" and "S" designations, which suggests that it has optical activity. The compound also contains methoxy groups, which are known for their aromatic and functional group properties. This chemical may have potential pharmaceutical or biological activity due to its complex structure and the presence of functional groups known to have biological effects. Further study and analysis are needed to fully understand its potential uses and effects.

Upstream product

• 17187-75-6 (+/-) podorhizone 
• 96548-65-1 3-(benzo[d][1,3]dioxol-5-ylmethyl)-4-methoxy-4-oxobutanoic acid 
• 70148-37-7 (S)-(-)-4-(3,4-methylenedioxybenzyl)dihydrofuran-2(3H)-one 
• 86-81-7 3,4,5-trimethoxy-benzaldehyde 
• 80483-34-7 4-(1,3-benzodioxol-5-ylmethyl)-4,5-dihydrofuran-2(3H)-one 
• 104485-87-2 (R)-(+)-α-(methylenedioxy-3,4 benzyl)hemisuccinate de methyle 
• 17187-77-8 (R)-(+)-3-piperonyl-4-butanolide 
• 84736-28-7 (methylenedioxy-3,4 benzylidene) α-hemisuccinate de methyle 
• 120-57-0 piperonal 
• 70381-90-7 (S)-(-)-α-(methylenedioxy-3,4 benzyl)hemisuccinate de methyle 
• 70381-89-4 methyl hydrogen (E)-2-<3,4-(methylenedioxy)benzylidene>succinate 
• 17187-78-9 (+/-) podorhizol 
• 17187-78-9 (+/-) epi-podorhizol 
• 103844-15-1 (3,4-dioxymethylenephenyl)methyl phenyl sulfide 

Downstream Products

• 17301-90-5 5-(3,4,5-trimethoxyphenyl)-5,8,8a,9-tetrahydro-5aH-furo[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6-one 
• 17187-81-4 (+)-isodeoxypodophyllotoxin 
• 477-51-0 rac-(7'β,8α,8'percentb)-3',4',5'-trimethoxy-4,5-methylenedioxy-2,7'-cyclolignan-9',9-olide 
• 17301-91-6 (3R*,4R*)-3-(3,4,5-trimethoxybenzyl)-4-(3,4-methylenedioxybenzyl)-4,5-dihydro-2(3H)-furanone 
• 17187-75-6 (+/-) podorhizone 
• 69222-20-4 (+/-)-isodesoxypodophyllotoxin 
• 477-51-0 (-)-isodesoxypodophyllotoxine 
• 477-51-0 (+)-isodesoxypodophyllotoxine 
• 17187-75-6 (+)-podorhizone 
• 17187-78-9 (+/-) epi-podorhizol 
• 17187-78-9 (+/-) podorhizol 
• 17187-79-0 (E)-4-(benzo[d][1,3]dioxol-5-ylmethyl)-3-(3,4,5-trimethoxybenzylidene)dihydrofuran-2(3H)-one 
• 72690-16-5 (3S,4S)-4-(benzo[d][1,3]dioxol-5-ylmethyl)-3-(3,4,5-trimethoxybenzyl)dihydrofuran-2(3H)-one 
• 6512-69-2 di-O-methylthujaplicantin methyl ether 

Relevant articles and documents

Stereoselective reactions. X. Total synthesis of optically pure antitumor lignan, burseran

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Diastereoselective synthesis of β-piperonyl-γ-butyrolactones from Morita-Baylis-Hillman adducts. highly efficient synthesis of (±)-yatein, (±)-podorhizol and (±)-epi-podorhizol

Starting from a Morita-Baylis-Hillman adduct we describe a simple and very efficient method for the diastereoselective preparation of hydroxylated β-piperonyl-γ-butyrolactones. To exemplify the efficiency of this approach we also describe a highly efficie

LIGNANES.10. PREPARATION DES (R)-(+) ET (S)-(-)-β-PIPERONYL ET β-VERATRYL-γ-BUTYROLACTONES ET LEUR UTILISATION DANS LA SYNTHESE TOTALE DE LIGNANES OPTIQUEMENT ACTIFS

A simple and efficient route leading to optically active β-benzyl-γ-butyrolactones is described.Thus, the methyl (R,S)-α-benzylhemisuccinate resulting from a Stobbe condensation with an appropriate aromatic aldehyde, followed by catalytic hydrogenation of the intermediate α-benzylidene hemisuccinic ester, was resolved by means of a chiral base (ephedrine or α-methyl benzylamine).Reduction of each enantiomer, using calcium borohydride, then led to the corresponding optically active β-benzyl-γ-butyrolactone.In this way, the following two lactones were obtained in both (R)-(+) and (S)-(-) enantiomeric forms, β-piperonyl- and β-veratryl-γ-butyrolactones 1 and 2 respectively.These lactones were used as key-intermediates for the syntheses of 17 optically active lignans and lignoids, such as (-)-dimethylmatairesinol (-)-23, (-)-kusunokinin (-)-26 and (+)-dimethylisolariciresinol (+)-35.