103853-77-6

Basic information

• Product Name: 2-hydroxy-2-methyl-N-benzylpropanamide
• Synonyms: 2-hydroxy-2-methyl-N-benzylpropanamide
• CAS NO: 103853-77-6
• Molecular Weight: 193.246
• Mol File: 103853-77-6.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 2-hydroxy-2-methyl-N-benzylpropanamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-hydroxy-2-methyl-N-benzylpropanamide(103853-77-6)
• EPA Substance Registry System: 2-hydroxy-2-methyl-N-benzylpropanamide(103853-77-6)

Safety Data

• Hazardous Substances Data: 103853-77-6(Hazardous Substances Data)

Upstream product

• 100-46-9 benzylamine 
• 80-55-7 ethyl 2-hydroxy-2,2-dimethylethanoate 
• 350255-13-9 1,2:5,6-di-O-isopropylidene-α-D-glucofuranose 
• 60110-37-4 N-benzyl-α-bromoisobutyranilide 
• 75-65-0 tert-butyl alcohol 
• 108-95-2 phenol 
• 594-61-6 2-methyllactic acid 
• 115539-43-0 4-benzyl-2,2-dimetyl-1-oxa-4,6-diazaspiro<4,4>nonan-3-one 
• 4064-06-6 1,2:3,4-di-O-isopropylidene-α-D-galactopyranose 
• 115539-47-4 1-(N-benzylcarbamoyl)-1-methylethyl 4'-aminobutanoate hydrochloride 
• 64-17-5 ethanol 

Downstream Products

• 1422432-17-4 C₁₁H₁₃NO₄S 
• 1422432-13-0 C₁₁H₁₃NO₃S 
• 91957-34-5 3-benzyl-5,5-dimethyl-4-methylene-2-oxazolidinone 
• 100192-61-8 3-benzyl-5,5-dimethyloxazolidine-2,4-dione 

Relevant articles and documents

Highly Efficient DMSO-Promoted α-Hydrolysis of α-Halohydroxamates under Mild Conditions

A novel and efficient method for the nucleophilic α-hydrolysis of α-halohydroxamates with water under metal-free conditions is described. In this reaction, the simple and readily available dimethyl sulfoxide (DMSO) was used as a catalyst, while water serv

MCF-supported boronic acids as efficient catalysts for direct amide condensation of carboxylic acids and amines

For efficient direct amide condensations, a new class of catalysts are developed by immobilizing boronic acids on mesocellular siliceous foam. Associated with their large pores, the microenvironments surrounding the immobilized active species greatly influence the catalytic activity. The fluoroalkyl moieties on the silica surface significantly enhance the catalytic performance along with easy recovery and reuse. This approach proposes a potential way to optimize various types of silica-supported catalysts. the Partner Organisations 2014.

On DABAL-Me3 promoted formation of amides

The range and utility of DABAL-Me3 couplings of methyl esters and free carboxylic acids with primary and secondary amines under a variety of conditions (reflux, sealed tube, microwave) has been compared for a significant range of coupling partners of relevance to the preparation of amides of interest in pharmaceutical chemistry. Commercial microwave reactors promote the fastest couplings and allow the use of significantly sterically hindered amines (primary and secondary) and carboxylic acids derivatives. The influence of microwave energy on the reaction system was shown to be typically related to thermal effects (over-pressuring and superheating).