103897-42-3Relevant academic research and scientific papers
Generation of 2-Carboethoxyethylzinc Iodide and 3-Carboethoxypropylzinc Iodide and Their Application to the Synthesis of γ- and δ-Keto Esters
Tamaru, Yoshinao,Ochiai, Hirofumi,Nakamura, Tatsuya,Tsubaki, Kazunori,Yoshida, Zen-ichi
, p. 5559 - 5562 (1985)
2-Carboethoxyethylzinc iodide and 3-carboethoxypropylzinc iodide are generated by the reaction of the corresponding iodoesters with Zn-Cu couple and utilized for the palladium catalyzed coupling reaction with acid chloride to quantitatively provide gamma- and delta- keto esters, respectively
Cu-based carbene involved in a radical process: A new crossover reaction to construct γ-peroxy esters and 1,4-dicarbonyl compounds
Jiang, Jiewen,Liu, Jiajun,Yang, Ling,Shao, Ying,Cheng, Jiang,Bao, Xiaoguang,Wan, Xiaobing
, p. 14728 - 14731 (2015)
Through merging Cu-based carbenes in a radical process, a novel crossover reaction has been successfully established, leading to the facile and efficient syntheses of various γ-peroxy esters and 1,4-dicarbonyl compounds. Considering that both Cu-based carbene complexes and radicals are extremely reactive, and therefore exist only in extraordinarily low concentrations, the high selectivity of this coupling reaction is unusual.
Synthesis of Unsymmetrical 1,4-Dicarbonyl Compounds by Photocatalytic Oxidative Radical Additions
Dong, Ya,Li, Ruining,Zhou, Junliang,Sun, Zhankui
, p. 6387 - 6390 (2021/08/23)
Herein we report a photocatalytic oxidative radical addition reaction for the synthesis of unsymmetrical 1,4-dicarbonyl compounds. This reaction utilizes a desulfurization process to generate electrophilic radicals, which add to α-halogenated alkenes and undergo further oxidation to deliver 1,4-dicarbonyl compounds. This mild and highly efficient method provides a valuable alternative to known strategies.
A process for preparing γ - ketone carbonyl compounds
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Paragraph 0154; 0155; 0156, (2018/07/30)
The present invention discloses a gamma-ketone carbonyl compound preparation method, wherein in the presence of an oxidizing agent, a styrene compound and ethyl diazoacetate are adopted as reactants, copper or a copper compound is adopted as a catalyst, DABCO is adopted as an alkali, and a free radical reaction is performed in a polar solvent isopropyl alcohol to obtain the product gamma-ketone carbonyl compound. According to the method of the present invention, the reaction activity of the catalyst is high, the reaction conditions are mild, the substrate application range is wide, the post-treatment is convenient, the yield of the target product is high, the preparation process is simple, and the sources of the used raw materials are wide.
ortho-halogeno substituents effect in asymmetric cyclization of 4-aryl-4-pentenals using a rhodium catalyst
Fujio, Masakazu,Tanaka, Masakazu,Wu, Xiao-Ming,Funakoshi, Kazuhisa,Sakai, Kiyoshi,Suemune, Hiroshi
, p. 881 - 882 (2007/10/03)
Asymmetric cyclization of 4-aryl-4-pentenals by using a cationic [Rh((R)-BINAP)]ClO4 afforded (3R)-3-substituted cyclopentanones; on the other hand, the cyclization of 4-pentenals bearing ortho-halogeno phenyl groups afforded the opposite (3S)-ones.
